Showing papers by "David Bergqvist published in 1983"
TL;DR: In 179 patients who had been studied after operation with FUT, a follow-up evaluation of FUT as an indicator of risk for development of deep venous insufficiency was made four to five years later, and no statistically significant differences were found in any of the parameters between legs that had been FUT-positive and those that were F UT-negative at the time of the operation.
Abstract: The 125I-fibrinogen uptake test (FUT) has been widely used in the past decade to detect postoperative thrombosis. FUT has been shown to correlate well with phlebography, and positive FUT is associated with a high frequency of pulmonary embolism. The long-term venous function of the leg after FUT-detected postoperative thrombosis, however, is inadequately documented. In 179 patients who had been studied after operation with FUT, a follow-up evaluation of FUT as an indicator of risk for development of deep venous insufficiency was made four to five years later. The patients replied to a questionnaire, were clinically examined, and underwent venous strain-gauge plethysmography, venous pressure measurement, and, in some cases, phlebography. No statistically significant differences were found in any of the parameters between legs that had been FUT-positive and those that were FUT-negative at the time of the operation. The frequency of deep venous insufficiency thus was equal in FUT-positive and FUT-negative legs. It was also independent of the site of FUT-detected thrombus in the leg.
11 citations
TL;DR: Tanned human umbilical vein grafts (Dardik Biograft, Meadox) were heparinized with tritium-labelled Heparin and Heparin was lost in contact with blood but the alcohol treatment delayedHeparin desorption significantly.
Abstract: Tanned human umbilical vein grafts (Dardik Biograft, Meadox) were heparinized with tritium-labelled heparin. Two methods of heparinization were undertaken: (1) incubation with heparin followed by ethyl alcohol 50% treatment, and (2) incubation with heparin without alcohol. Grafts were placed in the carotid arteries of sheep and removed 10 and 90 days later. Heparin was lost in contact with blood but the alcohol treatment delayed heparin desorption significantly.
9 citations
TL;DR: The HAUV showed a lower thrombogenicity than both the NHUV and the HsAUV grafts, and had the lowest 51Cr radioactivity.
Abstract: Nine glutaraldehyde-tanned human umbilical veins (GAUV) were incubated in heparin followed by storage in ethyl alcohol 50% (HAUV). These grafts were compared to five GAUV flushed with a heparinized solution without subsequent treatment in alcohol (HsAUV) and four nonheparinized GAUV (NHUV) placed in the contralateral carotid arteries of dogs for approximately 3 h. The thrombogenicity was evaluated by measuring the platelet adhesion and aggregation (51Cr), fibrinogen accumulation (125I-fibrinogen), the thrombus-free surface and the thrombus weight. The HAUV had the lowest 51Cr radioactivity. The means of thrombus-free surface and thrombus weight for the grafts were as follows: HAUV, 82% and 0.3 g (n = 9); HsAUV, 53% and 0.6 g (n = 5); NHUV, 13% and 1.2 g (n = 4). The HAUV showed a lower thrombogenicity than both the NHUV and the HsAUV grafts.
8 citations