Showing papers by "David Cohen published in 2005"

Specific genetic disorders and autism: clinical contribution towards their identification.

Abstract: Autism is a heterogeneous disorder that can reveal a specific genetic disease. This paper describes several genetic diseases consistently associated with autism (fragile X, tuberous sclerosis, Angelman syndrome, duplication of 15q11-q13, Down syndrome, San Filippo syndrome, MECP2 related disorders, phenylketonuria, Smith–Magenis syndrome, 22q13 deletion, adenylosuccinate lyase deficiency, Cohen syndrome, and Smith–Lemli–Opitz syndrome) and proposes a consensual and economic diagnostic strategy to help practitioners to identify them. A rigorous initial clinical screening is presented to avoid unnecessary laboratory and imaging studies. Regarding psychiatric nosography, the concept of “syndromal autism”—autism associated with other clinical signs—should be promoted because it may help to distinguish patients who warrant a multidisciplinary approach and further investigation.

The Cambridge Companion to Ancient Greek Law

Abstract: Part I. Law in Greece: 1. The unity of Greek law 2. Writing, law and written law Rosalind Thomas 3. Law and religion Robert Parker 4. Early Greek law Michael Gagarin Part II. Law in Athens I: Procedure: 5. Law and oratory at Athens Stephen Todd 6. Relevance in Athenian courts Adriaan Lanni 7. The influence of procedural choice on Athenian court-room strategies Lene Rubinstein 8. The role of the witness in Athenian law Gerhard Thur 9. Theories of punishment David Cohen 10. The rhetoric of law in fourth-century Athens Harvey Yunis Part III. Law in Athens II: Substantive Law: 11. Crime, punishment, and the rule of law in Classical Athens David Cohen 12. Gender, sexuality, and law Eva Cantarella 13. Family and property law Alberto Maffi 14. Athenian citizenship law Cynthia Patterson 15. Commercial law Edward E. Cohen Part IV. Law Outside Athens: 16. The Goryns laws John Davies 17. Greek law in foreign surroundings Hans-Alpert Rupprecht 18. Hellenistic law: general framework Joseph Meleze Modrzejewski Part V. Other Approaches to Greek Law: 19. Law, Attic comedy, and the regulation of comic speech Robert Wallace 20. Greek tragedy and law Danielle Allen 21. Law and political theory Josiah Ober 22. Law and nature in Greek thought A. A. Long.

Crime, Punishment, and the Rule of Law in Classical Athens

Abstract: INTRODUCTION The past two decades have seen a dramatic increase in scholarly research on aspects of the prosecution of crime in ancient Greece, and in particular in Athens. Scholarship has focused on the process of prosecution, the history and workings of courts such as the Areopagus, as well as specific crimes like homicide, adultery, theft, sycophancy, and hubris. Such research has enhanced our understanding of the procedures used in criminal prosecution and the substantive law of particular crimes. What has received far less attention, however, is the way in which Athenians conceptualized the category of “crime” and the laws enacted to deal with it. Did the Athenians in fact have conceptions of something like our notions of “crime” and “criminal,” as distinct from other types of wrongs and wrongdoers? Did they think of the methods of prosecuting and punishing criminal offenses as a separate legal category from other sorts of proceedings? Did they have a distinctive conception of punishment as opposed to other kinds of legal remedies? What did they believe were the distinguishing features of this area of the law and its relation to the larger framework of Athenian litigation and government? These are large and complex questions that could only be comprehensively answered in a book-length study.

Bailout use of platelet glycoprotein IIb-IIIa inhibition during coronary stent implantation: observations from the ESPRIT trial.

Abstract: Glycoprotein (GP) IIb/IIIa inhibitors are often used as a rescue or bailout therapy to manage complications arising during percutaneous coronary intervention, rather than as prophylactic treatment. We sought to identify the characteristics and outcomes of patients requiring bailout treatment. The ESPRIT trial randomized 2,064 patients to receive eptifibatide or placebo starting immediately before percutaneous coronary intervention (PCI). Bailout therapy was used in 77 patients: 43 (4.2%) randomized to placebo and 34 (3.3%) to eptifibatide (p = 0.3). Bailout therapy for thrombosis was used more often in the placebo group (2.1% versus 1.0%; p = 0.03). Multivariable predictors of bailout included a greater than or equal to 90% stenosis, or visible thrombus on the baseline angiogram, and no aspirin pre-treatment before PCI. However, overall the model predicted bailout poorly (c-index = 0.64). The need for bailout cannot be reliably predicted using baseline characteristics. Patients experiencing complications have poor clinical outcomes despite bailout use of GP IIb/IIIa inhibitors.

Medical errors--is total quality management for the battlefield desirable?

Abstract: There has recently been a great deal of discussion in both the lay press as well as the medical press regarding the incidence of errors that occur during medical practice. There have been many discussions of how quality control measures from industry can be applied to the health care system. Indeed both civilian and “brick and mortar” military medical treatment facilities are adapting these techniques. It is important that we understand the principles behind Total Quality Management (TQM) as well as its techniques and limitations. TQM is based on limiting deviation from an accepted standard of practice. These principles may be as applicable to our military health care facilities in a field environment as they are to our fixed facilities, although the standards used for measurement may have to be modified to adapt to different constraints of environment and resources. TQM techniques can nonetheless be applied in virtually any facility to ensure the best possible care and outcomes for our soldiers.