David J. Wilkinson

TL;DR: There is no clear consensus on the ideal method of repair for distal hypospadias and both the Mathieu and TIP techniques have been shown to have low rates of postoperative complications.

TL;DR: Findings support roles for both cFOS (indirect) and ATF3 (direct) in effecting MMP13 transcription in human chondrocytes.

TL;DR: The derivation of enteric nervous system progenitors in the aganglionic gut region of Hirschprung’s patients not only means that this tissue is a potential source of cells for future autologous transplantation, but it also raises the possibility of inducing the differentiation of these endogenous cells in situ to compensate for the Aganglionosis.

TL;DR: The results show a good outcome for most boys undergoing foreskin preputioplasty and intralesional triamcinolone for BXO, but rates of meatal stenosis may be reduced.

TL;DR: A series of recent studies are highlighted that describe how MMP-13 activity, and in fact that of other metalloproteinases, is in part controlled by receptor-mediated endocytosis, which provides a plethora of novel regulatory mechanisms, besides direct inhibition, which with renewed vigour could provide further therapeutic opportunities for regulating the activity of this class of important enzymes.