Showing papers by "Deborah A. Bilder published in 2018"
University of Colorado Denver1, Boston Children's Hospital2, University of Kentucky3, University of Pittsburgh4, University of Florida5, Children's Institute Inc.6, Oregon Health & Science University7, University of Utah8, BioMarin Pharmaceutical9, University of Texas Health Science Center at Houston10
TL;DR: Results from the PRISM Phase 3 program support the efficacy of pegvaliase for the treatment of adults with PKU, with a manageable safety profile in most participants.
99 citations
TL;DR: Social functioning outcomes mirror those reported previously for other samples, including samples with a high proportion of individuals with normal range intellectual abilities, with 20% achieving the most independent outcomes and 46% requiring high levels of support across most life areas.
Abstract: Adults with autism spectrum disorders (ASD) fall short of social outcomes of non-ASD peers in mid-life, as documented by currently published research. The aim of the current study was to extend what is known about social functioning, employment, independent living, and use of social services by examining details of the current life status for a population-based sample of adults with ASD (mean age = 35.5 years, range = 22.2-51.4). We collected outcome data via direct assessment and informant report for 169 individuals. Three-fourths of the sample had cognitive abilities in the intellectually disabled range. Social functioning outcomes, as a single measure, mirror those reported previously for other samples, including samples with a high proportion of individuals with normal range intellectual abilities, with 20% achieving the most independent outcomes and 46% requiring high levels of support across most life areas. Participant subgroups who achieved maximal outcomes represented a range of social and intellectual abilities for several outcome metrics. Participants used high levels of public and private supports, yet specific areas of clear, unmet need were also identified. Autism Res 2018, 11: 142-152. © 2017 International Society for Autism Research, Wiley Periodicals, Inc. Lay summary This paper describes the social functioning outcomes for 169 adults with autism spectrum disorders in mid-life. Adult participants spanned the full range of functional and cognitive ability levels, with over 75% functioning in the cognitively impaired range. While summary descriptions of outcomes for this sample were similar to those reported for other groups of adults, this report provides detailed information regarding employment outcomes, social relationships, leisure activities, participation in the community, residential situations, public service use, and involvement with law enforcement.
63 citations
18 Sep 2018
TL;DR: It was found that neonatal magnesium levels were not associated with decreased Autism spectrum disorder risk, and future research into autism spectrum disorder risks and treatments in premature infants is needed.
Abstract: Premature birth is associated with increased risk of autism spectrum disorder Antenatal maternal magnesium administration is known to reduce subsequent risk of cerebral palsy including among prema
6 citations