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Showing papers by "Deepak Sharma published in 2010"


Book ChapterDOI
07 Nov 2010
TL;DR: A Semantic-Web based framework is introduced, which provides an API for querying temporal information from clinical narratives and contains three major components: time normalizer, SWRL based reasoner, and OWL-DLbased reasoner.
Abstract: The ability to answer temporal-oriented questions based on clinical narratives is essential to clinical research. The temporal dimension in medical data analysis enables clinical researches on many areas, such as, disease progress, individualized treatment, and decision support. The Semantic Web provides a suitable environment to represent the temporal dimension of the clinical data and reason about them. In this paper, we introduce a Semantic-Web based framework, which provides an API for querying temporal information from clinical narratives. The framework is centered by an OWL ontology called CNTRO (Clinical Narrative Temporal Relation Ontology), and contains three major components: time normalizer, SWRL based reasoner, and OWL-DL based reasoner. We also discuss how we adopted these three components in the clinical domain, their limitations, as well as extensions that we found necessary or desirable to archive the purposes of querying time-oriented data from real-world clinical narratives.

46 citations


Journal ArticleDOI
TL;DR: Investigation of the antiepileptic effect of dehydroepiandrosterone treatment on iron-induced focal epileptiform activity in the rat brain revealed that DHEA attenuated the cognitive defects produced by epileptic activity.

23 citations


01 Jan 2010
TL;DR: Recent approaches to decontaminate human being from various harmful radiological agents in case of accidents or in cases of any terrorist attacks are RSDL (Reactive skin decontamination lotions), mobilizing agents, chelation therapy in caseof internal contamination through i.v, RSDecon lotion formulations.
Abstract: In the recent years there has been number of accidents which have been recorded worldwide with significant radioactive contamination. Radiation contamination can occur accidently or due to terrorists attack in the form of dirty bombs/nonconventional weapons. The release of radioactive materials with radiation has the potential of causing serious medical problems. Terrorist threats can results in internal and external radionuclide’s contamination of large number of population. Radiation contamination of human beings can cause acute as well as chronic and late illness and well known health hazards such as Acute Radiation Syndrome (ARS) (sometimes known as radiation poisoning or radiation sickness). The increasing use of radionuclides in medical diagnosis also raises the possibility of accidental spills and contamination. Recent approaches to decontaminate human being from various harmful radiological agents in case of accidents or in case of any terrorist attacks are RSDL (Reactive skin decontamination lotions), mobilizing agents, chelation therapy in case of internal contamination through i.v, RSDecon lotion formulations. Surface decontamination techniques by using soap and detergents

5 citations