D
Dennis C. Liotta
Researcher at Emory University
Publications - 372
Citations - 12124
Dennis C. Liotta is an academic researcher from Emory University. The author has contributed to research in topics: Receptor & NMDA receptor. The author has an hindex of 55, co-authored 354 publications receiving 11309 citations. Previous affiliations of Dennis C. Liotta include Yerkes National Primate Research Center & United States Department of Agriculture.
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Journal ArticleDOI
Inhibition of the replication of hepatitis B virus in vitro by 2',3'-dideoxy-3'-thiacytidine and related analogues.
TL;DR: Two 2',3'-dideoxy-3'-thiapyrimidine nucleosides were found to be the most potent anti-HBV compounds and both SddC and 5-FSddC should be further evaluated for the treatment of human HBV infection.
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Characterization of human immunodeficiency viruses resistant to oxathiolane-cytosine nucleosides.
Raymond F. Schinazi,R M Lloyd,M H Nguyen,D. L. Cannon,A McMillan,N Ilksoy,Chung K. Chu,Dennis C. Liotta,H Z Bazmi,John W. Mellors +9 more
TL;DR: Sequence analysis of amplified reverse transcriptase from a patient who had received (-)-BCH-189 therapy for 4 months demonstrated a mixture of the Met-184-to-Val (GTG) mutation and the parental genotype, indicating that theMet-184 mutation can occur in vivo.
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Thematic Review Series: Sphingolipids. Biodiversity of sphingoid bases (“sphingosines”) and related amino alcohols
Sarah T. Pruett,Sarah T. Pruett,Anatoliy S. Bushnev,Kerri Hagedorn,Madhura Adiga,Christopher A. Haynes,M. Cameron Sullards,Dennis C. Liotta,Alfred H. Merrill +8 more
TL;DR: The biodiversity of the backbones of sphingolipids and the broader field of naturally occurring and synthetic sphingoid base-like compounds, which vary in chain length, number, position, and stereochemistry of double bonds, hydroxyl groups, and other functionalities, are reviewed.
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Synthesis and biological evaluation of novel curcumin analogs as anti-cancer and anti-angiogenesis agents
Brian Adams,Eva M. Ferstl,Matthew C. Davis,Marike Herold,Serdar Kurtkaya,Richard F. Camalier,Melinda G. Hollingshead,Gurmeet Kaur,Edward A. Sausville,Frederick R. Rickles,James P. Snyder,Dennis C. Liotta,Mamoru Shoji +12 more
TL;DR: Compare analysis suggests the compound to be a possible RNA/DNA antimetabolite, but also implies that the compound's cytotoxicity may arise from a presently unknown mechanism.
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Quantitation of free sphingosine in liver by high-performance liquid chromatography.
TL;DR: The utility of the HPLC method was demonstrated with rat liver, providing the first quantitation of free sphingosine in this tissue of approximately 7 nmol/g wet wt, and lower limits of detection in the picomole range.