Showing papers by "Diederick E. Grobbee published in 1987"

Sodium restriction and potassium supplementation in young people with mildly elevated blood pressure.

Abstract: Forty young subjects, aged 18 to 28 years, with mildly elevated blood pressure participated in a double-blind randomized three-period crossover study of the effect of sodium restriction with and without potassium supplementation on blood pressure. Dietary sodium intake was restricted for 18 weeks in

Determinants of rise in blood pressure in normotensive children.

Abstract: Thirty-nine initially normotensive children (25 girls) with a large increase in systolic blood pressure (SBP) over a period of 7 years were compared with 78 children with a small increase, matched for age and gender. They were selected from a random sample of 596 Dutch children who were examined at an initial examination and 4 weeks later, and at yearly intervals thereafter. Body weight, height and Quetelet index at baseline were similar in children with a large rise in SBP and those with a small rise. Children with a large increase had a larger weight gain during follow-up than those with a small rise. Parental blood pressure (BP) and parental history of diabetes mellitus and cardiovascular diseases did not differ between the study groups. Cardiovascular reactivity as assessed by a cold-pressor test at baseline did not differ between the study groups, nor did urinary sodium excretion during follow-up. Total tobacco consumption was larger in those with a small increase. Children with a large rise in SBP experienced a larger fall in SBP from the initial to the 4-week examination. The individual variability of BP over the whole observation period did not differ between the study groups. These observations suggest that a fall in BP after a short follow-up period may be indicative of high BP in the years to come.