Trends in bioconversion of lignocellulose: Biofuels, platform chemicals & biorefinery concept

Fermentation of lignocellulosic hydrolysates. I: inhibition and detoxification

Mechanistic implications of plastic degradation

Biomass pyrolysis kinetics: A comparative critical review with relevant agricultural residue case studies

Poly-lactic acid synthesis for application in biomedical devices — A review

Social and economic development has driven considerable scientific and engineering efforts on the discovery, development and utilization of polymers. Polylactic acid (PLA) is one of the most promising biopolymers as it can be produced from nontoxic renewable feedstock. PLA has emerged as an important polymeric material for biomedical applications on account of its properties such as biocompatibility, biodegradability, mechanical strength and process ability. Lactic acid (LA) can be obtained by fermentation of sugars derived from renewable resources such as corn and sugarcane. PLA is thus an eco-friendly nontoxic polymer with features that permit use in the human body. Although PLA has a wide spectrum of applications, there are certain limitations such as slow degradation rate, hydrophobicity and low impact toughness associated with its use. Blending PLA with other polymers offers convenient options to improve associated properties or to generate novel PLA polymers/blends for target applications. A variety of PLA blends have been explored for various biomedical applications such as drug delivery, implants, sutures and tissue engineering. PLA and their copolymers are becoming widely used in tissue engineering for function restoration of impaired tissues due to their excellent biocompatibility and mechanical properties. The relationship between PLA material properties, manufacturing processes and development of products with desirable characteristics is described in this article. LA production, PLA synthesis and their applications in the biomedical field are also discussed.

https://sfamjournals.onlinelibrary.wiley.com/doi/pdf/10.1111/jam.14290

Polylactic acid: synthesis and biomedical applications.

Production of acidic lipase by Aspergillus niger in solid state fermentation

Strain improvement of Penicillium janthinellum NCIM 1171 for increased cellulase production.

Development of biocatalysts for production of commodity chemicals from lignocellulosic biomass.

Efficient lactic acid production from cane sugar molasses by Lactobacillus delbrueckii mutant Uc-3 in batch fermentation process is demonstrated. Lactic acid fermentation using molasses was not significantly affected by yeast extract concentrations. The final lactic acid concentration increased with increases of molasses sugar concentrations up to 190 g/liter. The maximum lactic acid concentration of 166 g/liter was obtained at a molasses sugar concentration of 190 g/liter with a productivity of 4.15 g/liter/h. Such a high concentration of lactic acid with high productivity from molasses has not been reported previously, and hence mutant Uc-3 could be a potential candidate for economical production of lactic acid from molasses at a commercial scale.

Digambar Gokhale

Papers

Polylactic acid: synthesis and biomedical applications.

Production of acidic lipase by Aspergillus niger in solid state fermentation

Strain improvement of Penicillium janthinellum NCIM 1171 for increased cellulase production.

Development of biocatalysts for production of commodity chemicals from lignocellulosic biomass.

Utilization of Molasses Sugar for Lactic Acid Production by Lactobacillus delbrueckii subsp. delbrueckii Mutant Uc-3 in Batch Fermentation