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Dimitrios Koutsimpelas

Researcher at University of Mainz

Publications -  20
Citations -  335

Dimitrios Koutsimpelas is an academic researcher from University of Mainz. The author has contributed to research in topics: Head and neck squamous-cell carcinoma & Vascular endothelial growth factor. The author has an hindex of 12, co-authored 19 publications receiving 307 citations.

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Promoter methylation of MGMT, MLH1 and RASSF1A tumor suppressor genes in head and neck squamous cell carcinoma: pharmacological genome demethylation reduces proliferation of head and neck squamous carcinoma cells

TL;DR: Promoter hypermethylation of the tumor suppressor genes MGMT and RASSF1A in HNSCC is shown, suggesting that this epigenetic inactivation of TSGs may play a role in the development of H NSCC.
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Expression of vascular endothelial growth factor and basic fibroblast growth factor in sporadic vestibular schwannomas correlates to growth characteristics.

TL;DR: The bFGF and VEGF mRNA expression and the bF GF and V EGF protein expression in sporadic VS correlates to the tumour volume, to the tumor growth index, and to the MVD, which might indicate an angiogenic and neurotrophic influence of these factors and a possible involvement in the growth of sporadic VS.
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Treatment for adult idiopathic and Wegener-associated subglottic stenosis.

TL;DR: Endoscopic laser surgery combined with local MMC and triamcinolone application and postoperative oral steroid/methotrexate and PPI therapy provides a treatment option that results in prolongation of the symptom-free time intervals and avoidance of open surgery in patients with idiopathic and Wegener-associated hard and short SGS.
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Endovascular carotid reconstruction in palliative head and neck cancer patients with threatened carotid blowout presents a beneficial supportive care measure.

TL;DR: A head and neck cancer patient receiving palliative care, presenting with threatened carotid blowout, who was managed with endovascular placement of a covered stent under elective conditions in order to prevent an inevitable carOTid rupture is introduced.
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Multifocal adult rhabdomyoma of the head and neck: a case report and literature review.

TL;DR: A rare case of a multifocal adult rhabdomyoma in a 72-year-old woman diagnosed with two lesions located in the area of the left aryepiglottic fold and the second right cervical arising from oesophagus is presented.