Ethnic Groups in Conflict

International Encyclopedia of the Social and Behavioral Sciences (vol. 10)

https://www.linkgroup.hu/docs/13PharmTher.pdf

Structure and dynamics of molecular networks: A novel paradigm of drug discovery: A comprehensive review

r 9HE purpose of this paper is to explore a hypothesis, based on acIcumulating evidence, regarding the character of inventions likely to issue from the research laboratories of the large industrial corporations. Simply put, this hypothesis may be stated as follows: with few exceptions, the large industrial laboratories are likely to be minor sources of major (radically new and commercially or militarily important) inventions; rather they are likely to be major sources of essentially "improvement" inventions. Put more precisely, the hypothesis states that the proportion of all minor inventions originating in the large industrial laboratories is likely to exceed the proportion of all major inventions originating in these laboratories. Note that the stress on the relative importance of these laboratories as sources of improvement inventions is not necessarily a denigration of the economic importance of this contribution. The cumulative effect of these improvement inventions may be, and often has been, of substantial importance over long periods of time for advancing technology, investment opportunities, and economic growth. The stress on improvement inventions as the principal product of the research laboratories of the large industrial corporations is meant simply to emphasize that, whatever the importance of their contributions, most of the latter is not likely to involve radically new inventive activity. I cannot claim originality for this hypothesis. After it suggested itself in the course of my investigations, I discovered that others, some of them in the most unlikely positions,2 had earlier said much the same thing. But, apart from occasional remarks, I can find no discussions attempting to explain or justify it. And because, if reasonably accurate, it has numerous ramifications, I have felt the need to set down an extended analysis of 1 I wish to thank members of the Seminar on Law and Technology, sponsored by the University of Wisconsin Law School under the auspices of the Ford Foundation, for their many helpful comments on this paper. Especially do I wish to thank Professors Jacob Schmookler, Robert Merrill, John Stedman, Harrison White, and John Heath. 2 See particularly the statement quoted below (p. 114) of D)r. Frank Jewett, former president of Bell Laboratories.

The journal of political economy

What manner of organization is the National Bureau of Economic Research? How does it select research topics? Who does the work and what kind of tasks do they perform? Where do the funds come from? How does the National Bureau safeguard the scientific quality of its findings? How are the results disseminated? Visitors to the National Bureau often ask these and similar questions; perhaps the answers will be of interest to readers of the American Statistician. The National Bureau of Economic Research is a private non-profit corporation, formed, according to its charter, "to conduct, or assist in the making of exact and impartial investigations in the field of economic, social and industrial science, and to this end to cooperate with governments, universities, learned societies, and individuals." Hence it is not a government agency, nor an adjunct of a university, nor does it sell research services. The revenue from the only products it does sell, publications, barely covers the printing costs. Its funds are contributed by philanthropic foundations, by trade and professional organizations, by business concerns, trade unions, and individuals. Contributions are usually on a yearly basis, but some grants cover several years. Some of the funds are earmarked for specific studies; the balance goes to support a general program of research. The National Bureau is governed by a Board of Directors numbering about thirty, selected to represent various institutions and diverse points of view on economic problems. Over the years since the Bureau was founded in 1920 this body of men has made a significant contribution to the development of scientific inquiry in economics, both within the National Bureau and outside. Such outstanding economists as Wesley C. Mitchell, George E. Roberts, Allyn A. Young, Edwin F. Gay, Thomas S. Adams, and John R. Commons have been among its members. At the present time professors from a dozen universities are on the Board. Also, Directors from each of the following organizations are elected: American Statistical Association, American Economic Association, American Farm Economic Association, Economic History Association, American Institute of Accountants, American Management Association, Congress of Industrial Organizations, and American Federation of Labor. Finally, there is a group of Directors at Large, men from varied walks of life with an abiding interest in economic research. The Board serves an important function not only in shaping the broad lines of the research program but also in safeguarding the quality of the results. Matters of policy requiring prompt action are handled by an Executive Committee of eleven, elected by the Board from its membership. Arthur F. Burns, the Director of Research, is the member of the Committee who is directly responsible for the research program. The members of the research staff, numbering about twenty-five, direct the individual studies, and are aided in their work by upwards of forty-five research assistants. A staff of typists, bookkeepers, mimeograph operators, etc., brings the total payroll of the National Bureau to roughly a hundred persons. William J. Carson, the Executive Director, handles the Bureau's finances, accounts, and other administrative matters. Not all the employees of the National Bureau work at the main office at 1819 Broadway, New York City. DuLr Financial Research Program is housed at "Hillside," an estate about 10 miles north of Manhattan overlooking the HuLdson River. Other National BureauL investigators are to be fotund at various universities throughout the United States, since cooperative arrangements are maintained with a number of universities that permit their facultv members to engage in National Butreau studies. Government agencies, too, cooperate in similar ways. Such cooperative relationships are a vital feature of our work, and we try to foster them in many ways. The growing acceptance on the part of universities of the view that research is part of the job of a faculty member has helped to make these efforts productive. For example, for a number of years we have appointed promising young men or women holding university positions as Research Associates for one year. The objective is to enable scholars to pursue their research interests in fields in which the National Bureau also has an interest. Since 1930 twenty-six Research Associates, coming from eighteen American colleges or universities and two foreign universities, have been appointed under the plan. The work of several committees is another example of cooperation for the purpose of advancing research. Two committees, one on financial and the other on fiscal research, help to guide our studies in these areas. They are composed of experts from universities, government agencies, and private business. In 1935 the Universities-National Bureau Committee was established for the express purpose of promoting contact

The National Bureau of Economic Research

Cellular transcription networks are conceptualized as distributed control systems that regulate gene expression.

https://science.sciencemag.org/content/sci/323/5917/1016.full.pdf

Attractors and Democratic Dynamics

We present a novel connection between binary search trees (BSTs) and points in the plane satisfying a simple property. Using this correspondence, we achieve the following results:1. A surprisingly clean restatement in geometric terms of many results and conjectures relating to BSTs and dynamic optimality.2. A new lower bound for searching in the BST model, which subsumes the previous two known bounds of Wilber [FOCS'86].3. The first proposal for dynamic optimality not based on splay trees. A natural greedy but offline algorithm was presented by Lucas [1988], and independently by Munro [2000], and was conjectured to be an (additive) approximation of the best binary search tree. We show that there exists an equal-cost online algorithm, transforming the conjecture of Lucas and Munro into the conjecture that the greedy algorithm is dynamically optimal.

/pdf/the-geometry-of-binary-search-trees-2v4dv49bvo.pdf

The geometry of binary search trees

We present an $O(\lg \lg n)$-competitive online binary search tree, improving upon the best previous (trivial) competitive ratio of $O(\lg n)$. This is the first major progress on Sleator and Tarjan’s dynamic optimality conjecture of 1985 that $O(1)$-competitive binary search trees exist.

/pdf/dynamic-optimality-almost-30s88gr3nh.pdf

Dynamic Optimality—Almost

Predicting panic is of critical importance in many areas of human and animal behavior, notably in the context of economics. The recent financial crisis is a case in point. Panic may be due to a specific external threat or self-generated nervousness. Here we show that the recent economic crisis and earlier large single-day panics were preceded by extended periods of high levels of market mimicry—direct evidence of uncertainty and nervousness, and of the comparatively weak influence of external news. High levels of mimicry can be a quite general indicator of the potential for self-organized crises.

/pdf/anticipating-economic-market-crises-using-measures-of-3cus3icsdn.pdf

Anticipating Economic Market Crises Using Measures of Collective Panic

A method for organizing, visualizing, and navigating data objects within a dataset is presented, including network visualization alongside a detailed information display. The method includes interactivity with the visualization through network panning, zooming, and node clicking. The network nodes represent the data objects. Node proximity and links represent similarity or other relatedness measures between respective data objects. The network can be displayed in full to illustrate large scale properties. Clicking the nodes provides further data object information of the highlighted node, which is displayed alongside the network.

Dion Harmon

Papers

Attractors and Democratic Dynamics

The geometry of binary search trees

Dynamic Optimality—Almost

Anticipating Economic Market Crises Using Measures of Collective Panic

Method and apparatus for dynamic information visualization