D
Dionisios Chrysis
Researcher at University of Patras
Publications - 64
Citations - 2402
Dionisios Chrysis is an academic researcher from University of Patras. The author has contributed to research in topics: Apoptosis & Medicine. The author has an hindex of 24, co-authored 57 publications receiving 2157 citations. Previous affiliations of Dionisios Chrysis include University of North Carolina at Chapel Hill & Boston Children's Hospital.
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Clinical phenotype and mutant TRα1
Alies van Mol-van Mullem,Ramona van Heerebeek,Dionisios Chrysis,Edward Visser,Marco Medici,Maria Andrikoula,Agathocles Tsatsoulis,Robin P. Peeters,Theo J. Visser +8 more
TL;DR: A father and daughter with a mutation in the nuclear receptor gene for thyroid hormone have abnormal levels of thyroid hormone, normal thyrotropin levels, growth retardation, and mildly delayed motor and cognitive development.
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Interleukin-1β and TNF-α Act in Synergy to Inhibit Longitudinal Growth in Fetal Rat Metatarsal Bones†
TL;DR: In a model of cultured fetal rat metatarsal bones, it is found that IL‐1β and TNF‐α act in synergy to inhibit longitudinal growth, an effect linked to decreased proliferation and increased apoptosis of growth plate chondrocytes and IGF‐I could partially reverse all these effects.
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Insulin-Like Growth Factor-I Overexpression Attenuates Cerebellar Apoptosis by Altering the Expression of Bcl Family Proteins in a Developmentally Specific Manner
TL;DR: The data show that IGF-I exerts anti-apoptotic actions during cerebellar development, and thereby alters the magnitude of naturally occurring apoptosis, and appears to affect multiple steps in the apoptotic pathway in a developmentally specific manner.
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Doxorubicin Induces Apoptosis in Germ Line Stem Cells in the Immature Rat Testis and Amifostine Cannot Protect against This Cytotoxicity
Mi Hou,Dionisios Chrysis,Mirja Nurmio,Martti Parvinen,Staffan Eksborg,Olle Söder,Kirsi Jahnukainen +6 more
TL;DR: Observations suggest that the initiation phase of spermatogenesis is highly sensitive to doxorubicin-induced apoptosis, which results in a decrease in the size of the pool of germ-line stem cells.
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Localization of estrogen receptors-alpha and -beta and androgen receptor in the human growth plate at different pubertal stages.
Ola Nilsson,Dionisios Chrysis,Olli Pajulo,Anders Boman,Mikael Holst,Joanna Rubinstein,E. Martin Ritzén,Lars Sävendahl +7 more
TL;DR: The findings suggest that ERalpha, ERbeta and AR are expressed in the human growth plate throughout pubertal development, with no difference between the sexes.