D
Dirk Classen-Houben
Researcher at Hoffmann-La Roche
Publications - 15
Citations - 88
Dirk Classen-Houben is an academic researcher from Hoffmann-La Roche. The author has contributed to research in topics: Prodrug & Enantiomer. The author has an hindex of 5, co-authored 15 publications receiving 84 citations.
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Patent
Compounds and pharmaceutical compositions for the treatment of negative-sense ssrna virus infections
Dirk Classen-Houben,Oliver Szolar,Peter Sehr,Bernd Wendt,Delphine Gulligay,Stephen Cusack,Joe Lewis +6 more
TL;DR: The present invention relates to novel compounds and pharmaceutical compositions and the use thereof for the manufacture of a medicament for treating, ameliorating, or preventing disease conditions caused by a viral infection with negative-sense ssRNA viruses.
Patent
7-oxo-thiazolopyridine carbonic acid derivatives and their use in the treatment, amelioration or prevention of a viral disease
Andrea Wolkerstorfer,Oliver Szolar,Norbert Handler,Stephen Cusack,Thibault Sauvaître,Céline Simon,Christophe Morice,Bruno Giethlen,Thierry Langer,Mark D. Smith,Sung-Sau So,Dirk Classen-Houben,Helmut Buschmann +12 more
TL;DR: A compound having the general formula (A), optionally in the form of a pharmaceutically acceptable salt, solvate, polymorph, codrug, cocrystal, prodrug, tautomer, racemate, enantiomer or mixture thereof, which are useful in treating, ameloriating or preventing a viral disease is defined in this paper.
Patent
Heteroaryl hydroxamic acid derivatives and their use in the treatment, amelioration or prevention of a viral disease
Dirk Classen-Houben,Andrea Wolkerstorfer,Oliver Szolar,Mark D. Smith,Sung-Sau So,Stephen Cusack,Thierry Langer,Bruno Giethlen,Christophe Morice,Céline Michaut-Simon,Chloe Zubieta +10 more
TL;DR: A compound having the general formula I, optionally in the form of a pharmaceutically acceptable salt, solvate, polymorph, prodrug, tautomer, racemate, enantiomer or mixture thereof, which is useful in treating, ameloriating or preventing a viral disease is described in this paper.
Patent
Pyrimidin-4-one derivatives and their use in the treatment, amelioration or prevention of a viral disease
Dirk Classen-Houben,Andrea Wolkerstorfer,Oliver Szolar,Mark D. Smith,Sung-Sau So,Stephen Cusack,Thierry Langer,Bruno Giethlen,Christophe Morice,Céline Michaut-Simon,Laurence Jung +10 more
TL;DR: A compound having the general formula (II), optionally in the form of a pharmaceutically acceptable salt, solvate, polymorph, prodrug, tautomer, racemate, enantiomer, or diastereomer or mixture thereof, which is useful in treating, ameloriating or preventing a viral disease is described in this article.
Patent
7-oxo-4,7-dihydro-pyrazolo [1,5-a] pyrimidine derivatives which are useful in the treatment, amelioration or prevention of a viral disease
Andrea Wolkerstorfer,Oliver Szolar,Norbert Handler,Stephen Cusack,Thibault Sauvaître,Céline Simon,Christophe Morice,Bruno Giethlen,Thierry Langer,Mark D. Smith,Sung-Sau So,Dirk Classen-Houben,Helmut Buschmann +12 more
TL;DR: In this article, a compound having the general formula (C) is defined as a compound that is useful in treating, ameloriating or preventing a viral disease, and specific combination therapies are disclosed.