The synthesis of metal oxide nanoparticles with the use of medicinal plant extract is a promising alternative to the conventional chemical method. This work aimed to synthesize zinc oxide nanoparticles using a green approach from indigenous “Koseret” Lippia adoensis leaf extract which is an endemic medicinal plant and cultivated in home gardens of different regions of Ethiopia. The biosynthesized zinc oxide nanoparticles were characterized using thermogravimetric analysis, X-ray diffraction, scanning electron microscopy-energy dispersive spectroscopy, transmission electron microscopy, ultraviolet-visible spectroscopy, and Fourier transform infrared spectroscopy. Furthermore, this study also evaluated the antibacterial activity of the synthesized ZnO nanoparticles against clinical and standard strains of Escherichia coli, Klebsiella pneumonia, Staphylococcus aureus, and Enterococcus faecalis by the disc diffusion method. According to the result of this study, ZnO nanoparticles synthesized using Lippia adoensis leaf extract showed promising result against both Gram-positive and Gram-negative bacterial strains with a maximum inhibition zone of 14 mm and 12 mm, respectively, using uncalcinated form of the synthesized ZnO nanoparticles.

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Synthesis of Zinc Oxide Nanoparticles Using Leaf Extract of Lippia adoensis (Koseret) and Evaluation of Its Antibacterial Activity

Zinc oxide nanoparticles (ZnO NPs) are one of the prominent metal oxide nanoparticles with significant applications in many industries and research institutes. Various methods of synthesis have been adopted in the production of ZnO NPs so as to meet its high demand. The environmental implications and economic challenges attached to most of the means of ZnO NPs synthesis have resulted in the quest for other alternatives with environmental and economic benefits. Interestingly, the biological method of synthesis using plant sources have been found appropriate for the production of ZnO NPs dues to its numerous health, environmental, economic, and medicinal benefits. The distinctive features of ZnO NPs synthesized using plant extracts enhanced its application in agriculture for the production of fertilizers, pesticides, and fumigants. In the field of medicine and pharmacy, phytosynthesized ZnO NPs have gained remarkable usage in the production of disinfectant, antifungal, anticancer, antioxidant, anti-inflammatory and antidiabetics agents. Despite the enlisted benefits of biosynthesized ZnO NPs, the difficulties associated with the elucidation of formation mechanism and reactions still remain unraveled. This review described the summary of the recent advances in the synthesis, mechanism routes, characterization techniques, and applications of biosynthesized ZnO NPS in agriculture, medicine, and textile industries.

A Review on Green Synthesis of Zinc Oxide Nanoparticles Using Plant Extracts and Its Biomedical Applications

Facile one-step green synthesis of gold nanoparticles (AuNp) using licorice root extract: Antimicrobial and anticancer study against HepG2 cell line

Zinc oxide nanoparticles (ZnO NPs) are considered as very significant and essential material due to its multifunctional properties, stability, low cost and wide usage. Many green and biogenic approaches for ZnO NPs synthesis have been reported using various sources such as plants and microorganisms. Plants contain biomolecules that can act as capping, oxidizing and reducing agents that increase the rate of reaction and stabilizes the NPs. This review emphasizes and compiles different types of plants and parts of plant used for the synthesis of ZnO and its potential applications at one place. The influence of biogenic and phytogenic synthesized ZnO on its properties and possible mechanisms for its fabrication has been discussed. This review also highlights the potential applications and future prospects of phytogenic synthesized ZnO in the field of energy production and storage, sun light harvesting, environmental remediation, and biological applications.

Zinc oxide and zinc oxide-based nanostructures: biogenic and phytogenic synthesis, properties and applications

The key pathways for synthesizing nanoparticles are physical and chemical, usually expensive and possibly hazardous to the environment. In the recent past, the evaluation of green chemistry or biological techniques for synthesizing metal nanoparticles from plant extracts has drawn the attention of many researchers. The literature on the green production of nanoparticles using various metals (i.e., gold, silver, zinc, titanium and palladium) and plant extracts is discussed in this study. The generalized mechanism of nanoparticle synthesis involves reduction, stabilization, nucleation, aggregation and capping, followed by characterization. During biosynthesis, major difficulties often faced in maintaining the structure, size and yield of particles can be solved by monitoring the development parameters such as temperature, pH and reaction period. To establish a widely accepted approach, researchers must first explore the actual process underlying the plant-assisted synthesis of a metal nanoparticle and its action on others. The green synthesis of NPs is gaining attention owing to its facilitation of the development of alternative, sustainable, safer, less toxic and environment-friendly approaches. Thus, green nanotechnology using plant extract opens up new possibilities for the synthesis of novel nanoparticles with the desirable characteristics required for developing biosensors, biomedicine, cosmetics and nano-biotechnology, and in electrochemical, catalytic, antibacterial, electronics, sensing and other applications.

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Divya Kalra

Papers

Green synthesis, characterization and anti microbial activities of ZnO nanoparticles using Euphorbia hirta leaf extract