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Donald J. McNamara
Researcher at Rockefeller University
Publications - 33
Citations - 1327
Donald J. McNamara is an academic researcher from Rockefeller University. The author has contributed to research in topics: Cholesterol & Sterol. The author has an hindex of 18, co-authored 33 publications receiving 1315 citations. Previous affiliations of Donald J. McNamara include Memorial Sloan Kettering Cancer Center & University of Nebraska Medical Center.
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Journal ArticleDOI
Heterogeneity of cholesterol homeostasis in man. Response to changes in dietary fat quality and cholesterol quantity.
Donald J. McNamara,R Kolb,Thomas S. Parker,H Batwin,Paul Samuel,Clinton D. Brown,E. H. Ahrens +6 more
TL;DR: The results demonstrate that the responses to dietary cholesterol and fat are highly individualized and that most individuals have effective feedback control mechanisms.
Journal ArticleDOI
Plasma mevalonate as a measure of cholesterol synthesis in man.
Thomas S. Parker,Donald J. McNamara,Clinton D. Brown,R Kolb,E. H. Ahrens,A W Alberts,J Tobert,J Chen,P J De Schepper +8 more
TL;DR: The hypothesis that short-term regulation of H MG-CoA reductase in tissues is quickly reflected by corresponding variations in plasma MVA was tested by using a specific inhibitor of HMG- coenzyme A reduct enzyme, mevinolin, to block MVA synthesis.
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Mevalonic acid in human plasma: relationship of concentration and circadian rhythm to cholesterol synthesis rates in man.
Thomas S. Parker,Donald J. McNamara,Clinton D. Brown,Owen Garrigan,R Kolb,Hedda Batwin,E.H. Ahrens +6 more
TL;DR: The presence in human plasma of MVA, an obligate precursor of cholesterol, in amounts apparent related to the rate of cholesterol synthesis offers a noninvasive, nonisotopic method for studying cholesterol synthesis in man.
Journal ArticleDOI
Portacaval shunt in patients with familial hypercholesterolemia.
Thomas E. Starzl,H. Chase,Edward Ahrens,Donald J. McNamara,David W. Bilheimer,Ernst J. Schaefer,Jean Rey,Kendrick A. Porter,Evan A. Stein,Antonio Francavilla,Leland Benson +10 more
TL;DR: Portacaval shunt has been effective therapy for patients with FH who were refractory or intolerant to medical treatment; it should be performed before the development of irreversible cardiovascular damage.
Journal ArticleDOI
Thin-layer and gas-liquid chromatographic identification of neutral steroids in human and rat feces
TL;DR: Natural steroids from rat and human feces were fractionated by sequential thin-layer chromatography on Florisil, silica gel, and silver nitrate-impregnatedsilica gel and analyzed by gas--liquid chromatography (GLC).