D
Dong Yang
Researcher at University of Tennessee Health Science Center
Publications - 16
Citations - 588
Dong Yang is an academic researcher from University of Tennessee Health Science Center. The author has contributed to research in topics: Mycobacterium tuberculosis & Tuberculosis. The author has an hindex of 9, co-authored 16 publications receiving 319 citations. Previous affiliations of Dong Yang include University of Michigan.
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Journal ArticleDOI
TLR2 senses the SARS-CoV-2 envelope protein to produce inflammatory cytokines.
Min Zheng,Rajendra Karki,Evan P. Williams,Dong Yang,Elizabeth A. Fitzpatrick,Peter Vogel,Colleen B. Jonsson,Thirumala-Devi Kanneganti +7 more
TL;DR: In this paper, both TLR2 and Myd88 expression were associated with COVID-19 disease severity, and they were found to be required for β-coronavirus-induced inflammatory responses.
Journal ArticleDOI
Simultaneous detection of isoniazid, rifampin, and ethambutol resistance of Mycobacterium tuberculosis by a single multiplex allele-specific polymerase chain reaction (PCR) assay.
Zhenhua Yang,Riza Durmaz,Dong Yang,Selami Günal,Lixin Zhang,Betsy Foxman,Ahmet Sanic,Carl F. Marrs +7 more
TL;DR: A multiplex allele-specific polymerase chain reaction (MAS-PCR) that detects the most commonly observed isoniazid, rifampin, and ethambutol resistance-associated mutations in a single assay provides a rapid, potentially more cost-effective, method of detecting multidrug-resistant TB.
Journal ArticleDOI
Clinical relevance of Mycobacterium tuberculosis plcD gene mutations.
Zhenhua Yang,Dong Yang,Ying Kong,Lixin Zhang,Carl F. Marrs,Betsy Foxman,Joseph H. Bates,F. Wilson,M. Donald Cave +8 more
TL;DR: Findings suggest that the plcD gene of M. tuberculosis is potentially involved in the pathogenesis of TB, and the clinical presentation of the disease may be influenced by the genetic variability of theplcD region.
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DNA Polymorphisms in the pepA and PPE18 Genes among Clinical Strains of Mycobacterium tuberculosis: Implications for Vaccine Efficacy
Andrea M. Hebert,Sarah Talarico,Dong Yang,Riza Durmaz,Carl F. Marrs,Lixin Zhang,Betsy Foxman,Zhenhua Yang +7 more
TL;DR: Investigation of the genomic diversity of the pepA and PPE18 genes among 225 clinical strains of M. tuberculosis found many of the changes occurred in regions previously reported to be potential T-cell epitopes, suggesting immunity induced by Mtb72F may not recognize a proportion ofM.
Journal ArticleDOI
Distribution of Insertion- and Deletion-Associated Genetic Polymorphisms among Four Mycobacterium tuberculosis Phospholipase C Genes and Associations with Extrathoracic Tuberculosis: a Population-Based Study
Ying Kong,M. D. Cave,Dong Yang,Lixin Zhang,Carl F. Marrs,Betsy Foxman,Joseph H. Bates,F. Wilson,Leonard Mukasa,Zhenhua Yang +9 more
TL;DR: The data suggest that the plcD gene might play a more important role in the pathogenesis of thoracic TB than it does in the Pathogenesis of extrathoracic tuberculosis.