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Donglai Chen
Researcher at Tongji University
Publications - 68
Citations - 695
Donglai Chen is an academic researcher from Tongji University. The author has contributed to research in topics: Lung cancer & Adenocarcinoma. The author has an hindex of 11, co-authored 62 publications receiving 375 citations.
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Journal ArticleDOI
Tumor Spread through Air Spaces Affects the Recurrence and Overall Survival in Patients with Lung Adenocarcinoma >2 to 3 cm
Chenyang Dai,Huikang Xie,Hang Su,Yunlang She,Erjia Zhu,Ziwen Fan,F. Zhou,Yijiu Ren,Dong Xie,Hui Zheng,Xiermaimaiti Kadeer,Donglai Chen,Liping Zhang,Gening Jiang,Chunyan Wu,Chang Chen +15 more
TL;DR: Preliminary evidence is provided that STAS could be considered as a factor in a staging system to predict prognosis more precisely, especially in ADCs larger than 2 to 3 cm.
Journal ArticleDOI
Tumor Spread Through Air Spaces in Non-Small Cell Lung Cancer: A Systematic Review and Meta-Analysis.
Donglai Chen,Yiming Mao,Yiming Mao,Junmiao Wen,Yunlang She,Erjia Zhu,Feng Zhu,Yongsheng Zhang,Min Fan,Chang Chen,Yongbing Chen +10 more
TL;DR: It is indicated that tumor STAS was a potentially significant prognostic predictor for surgical patients with NSCLCs and further large-scale prospective studies are warranted to confirm the prognostic significance of STAS in patients withNSCLCs.
Journal ArticleDOI
M2 macrophage-derived exosomal long non-coding RNA AGAP2-AS1 enhances radiotherapy immunity in lung cancer by reducing microRNA-296 and elevating NOTCH2.
TL;DR: In this paper, the effect of AGAP2-AS1 and miR-296/notch homolog protein 2 (NOTCH2) axis on the progression and radioresistance of lung cancer was identified.
Journal ArticleDOI
Biodegradable Nanoparticles Mediated Co-delivery of Erlotinib (ELTN) and Fedratinib (FDTN) Toward the Treatment of ELTN-Resistant Non-small Cell Lung Cancer (NSCLC) via Suppression of the JAK2/STAT3 Signaling Pathway.
Donglai Chen,Fuquan Zhang,Jinhui Wang,Hua He,Shanzhou Duan,Rongying Zhu,Chang Chen,Lichen Yin,Yongbing Chen +8 more
TL;DR: A synergistic anti-cancer effect was achieved by PEG-PLA NPs encapsulating both ELTN and FDTN in ELTN-resistant NSCLC tumors both in vitro and in vivo, and lower systemic side effect was noted for the co-delivery NPs compared to free drugs.
Journal ArticleDOI
A Proposal for Restaging of Invasive Lung Adenocarcinoma Manifesting as Pure Ground Glass Opacity.
Rui Mao,Yunlang She,Erjia Zhu,Donglai Chen,Chenyang Dai,Chunyan Wu,Huikang Xie,Huiyuan Zhu,Ke Fei,Chang Chen +9 more
TL;DR: IAC radiologically manifesting as pure GGO is a group of tumors with low-grade malignancies and excellent prognosis and external validation is needed to assess whether it should be restaged in the TNM classification of non-small lung cancers.