D
Duane D. Miller
Researcher at University of Tennessee Health Science Center
Publications - 498
Citations - 16517
Duane D. Miller is an academic researcher from University of Tennessee Health Science Center. The author has contributed to research in topics: Androgen receptor & Receptor. The author has an hindex of 64, co-authored 490 publications receiving 14976 citations. Previous affiliations of Duane D. Miller include GTx, Inc. & University of Tennessee.
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An Overview of Tubulin Inhibitors That Interact with the Colchicine Binding Site
TL;DR: The present review is a synopsis of compounds that have been reported in the past decade that have provided an increase in understanding of the actions of CBSIs.
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Structural basis for antagonism and resistance of bicalutamide in prostate cancer.
TL;DR: The three-dimensional structure demonstrates that the B ring of R-bicalutamide in the W741L mutant is accommodated at the location of the indole ring of Trp-741 in the WT AR bound to dihydrotestosterone.
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Emerging Trends in Oral Delivery of Peptide and Protein Drugs
TL;DR: This review focuses on the challenges posed by the GI system and how different pharmaceutical approaches can be used to make oral delivery of protein and peptide drugs more feasible.
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Selective androgen receptor modulators in preclinical and clinical development
TL;DR: This review summarizes the current standing of research and development of Selective androgen receptor modulators, crystallography of AR with SARMs, plausible mechanisms for their action and the potential therapeutic indications for this emerging class of drugs.
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The role of vitamin D in cancer prevention
TL;DR: Preclinical data strongly support a role for vitamin D in the prevention of cancer through its anti-proliferative, pro-apoptotic, and anti-angiogenic effects on cells.