Neurodegenerative diseases involve a heterogeneous group of disorders characterized by progressive impairment and degeneration of nerve structure and function, eventually leading towards the death of certain parts of the CNS and brain. The most common form of neurodegenerative diseases includes Alzheimer’s disease (AD) leading towards progressive loss of memory, Parkinson’s disease (PD) causing impairment in movements, Huntington’s disease (HD) affecting the ability to walk, talk and think. The pathogenesis of these diseases mainly AD and PD are complex and there is no such cure for these diseases as the drugs that are currently in use shown to have an adverse effect on these diseases. However epidemiological studies have shown that consumption of tea has therapeutic effects in treating those neurodegenerative diseases especially the major tea components i.e. Catechins, Caffeine, Theanine, TFs in elderly persons. The major tea components are antioxidants which help to combat oxidative stress, the major reason behind all those neurodegenerative diseases, regulating signaling pathways as well as helps in metal chelation. The objective of this review is to summarize all the available information on different bioactive components of tea in the treatment of different neurodegenerative diseases.

Dwaipee De

Papers

Role of Tea and Its Components in Treatment of Neurodegenerative Diseases: A Review