E
E. H. Sage
Researcher at Veterans Health Administration
Publications - 1
Citations - 115
E. H. Sage is an academic researcher from Veterans Health Administration. The author has contributed to research in topics: Endothelial stem cell & Endothelium. The author has an hindex of 1, co-authored 1 publications receiving 113 citations.
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SPARC (secreted protein acidic and rich in cysteine) regulates endothelial cell shape and barrier function.
TL;DR: It is proposed that SPARC regulates endothelial barrier function through F-actin-dependent changes in cell shape, coincident with the appearance of intercellular gaps, that provide a paracellular pathway for extravasation of macromolecules.