E
E. Sutherland
Researcher at University of Colorado Denver
Publications - 2
Citations - 161
E. Sutherland is an academic researcher from University of Colorado Denver. The author has contributed to research in topics: Na+/K+-ATPase & Membrane fluidity. The author has an hindex of 2, co-authored 2 publications receiving 160 citations.
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Ethinylestradiol administration selectively alters liver sinusoidal membrane lipid fluidity and protein composition.
TL;DR: Administration of high-dose ethinylestradiol to rats decreases bile flow, Na,K-ATPase specific activity, and liver plasma membrane fluidity, while Liver plasma membrane fractions showed no change in free cholesterol or cholesterol/phospholipid molar ratio.
Journal ArticleDOI
Biochemical localization of hepatic surface-membrane Na+,K+-ATPase activity depends on membrane lipid fluidity.
TL;DR: Findings suggest that hepatic Na+,K+-ATPase is distributed in both surface membranes but functions more efficiently and, perhaps, specifically in the sinusoidal membranes because of their higher bulk lipid fluidity.