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Showing papers by "Edward S. Cole published in 1985"



Patent
01 Oct 1985
TL;DR: A replicable expression vector capable, in a transformed host mammallian cell, of expressing a DNA sequence encoding active human TPA, which, when expressed in the host cell, yields active TPA which lacks one or more of the TPA-bound N-linked carbohydrate moieties of naturally occurring human tPA.
Abstract: A replicable expression vector capable, in a transformed host mammallian cell, of expressing a DNA sequence encoding active human TPA which, when expressed in the host cell, yields active TPA which lacks one or more of the TPA-bound N-linked carbohydrate moieties of naturally occurring human TPA.

8 citations