Efrem D. Mandelcorn

TL;DR: This comprehensive article reviews these adverse events of systemic corticosteroid therapy and provides practical recommendations for their prevention and management based on both current literature and the clinical experience of the authors.

TL;DR: Repeated use of topical moxifloxacin after IVT injection significantly increases antibiotic resistance of ocular surface flora, and it is recommended that routine use of prophylactic antibiotics afterIVT injection be discouraged.

TL;DR: A 36-year-old woman treated with the anti PD-1 antibody Pembrolizumab for metastatic cutaneous melanoma in the first line setting achieved a complete response and then relapsed with metastases to the vitreous cavity with an associated angiographically determined retinal vasculitis, highlighting the need for immune sanctuary sites to be monitored in the presence ofPD-1 inhibition.

TL;DR: In eyes with persistent or recurrent idiopathic macular holes after standard PPVs with internal limiting membrane peeling, repeat PPV with subretinal balanced salt solution injection to create a macular detachment may be a viable surgical treatment option.

TL;DR: Macular decompression by internal limiting membrane (ILM) peeling may reduce macular edema and hemorrhage and improve visual acuity by relieving elevated intraretinal tissue pressure and facilitating egress of blood and extracellular fluid out of inner retinal layers into the vitrectomized vitreous cavity.