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Elana H. Super
Researcher at Wyss Institute for Biologically Inspired Engineering
Publications - 4
Citations - 594
Elana H. Super is an academic researcher from Wyss Institute for Biologically Inspired Engineering. The author has contributed to research in topics: Mannan-binding lectin & Bacterial cell structure. The author has an hindex of 3, co-authored 3 publications receiving 437 citations. Previous affiliations of Elana H. Super include Harvard University.
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Journal ArticleDOI
A bioinspired omniphobic surface coating on medical devices prevents thrombosis and biofouling
Daniel C. Leslie,Anna Waterhouse,Julia B Berthet,Julia B Berthet,Julia B Berthet,Thomas M. Valentin,Alexander Watters,Alexander Watters,Abhishek Jain,Philseok Kim,Benjamin Hatton,Benjamin Hatton,Benjamin Hatton,Arthur Nedder,Kathryn Donovan,Elana H. Super,Caitlin Howell,Caitlin Howell,Christopher P Johnson,Christopher P Johnson,Thy L. Vu,Thy L. Vu,Dana Bolgen,Sami A. Rifai,Anne Hansen,Michael Aizenberg,Michael Super,Michael Super,Michael Super,Joanna Aizenberg,Donald E. Ingber +30 more
TL;DR: A bioinspired, omniphobic coating is applied to tubing and catheters and it is shown that it completely repels blood and suppresses biofilm formation, which could reduce the use of anticoagulants in patients and help to prevent thrombotic occlusion and biofouling of medical devices.
Journal ArticleDOI
Broad-spectrum capture of clinical pathogens using engineered Fc-mannose-binding lectin enhanced by antibiotic treatment.
Benjamin T. Seiler,Mark Cartwright,Alexandre L. M. Dinis,Shannon C Duffy,Patrick Lombardo,David Cartwright,Elana H. Super,Jacqueline Lanzaro,Kristen Dugas,Michael Super,Michael Super,Donald E. Ingber,Donald E. Ingber,Donald E. Ingber +13 more
TL;DR: The efficiency of pathogen detection and variation between binding of different strains of the same species could be improved by treating the bacteria with antibiotics, or mechanical disruption using a bead mill prior to FcMBL capture to reveal previously concealed binding sites within the bacterial cell wall.
Posted ContentDOI
Broad spectrum capture of clinical pathogens using engineered Fc-Mannose-Binding Lectin (FcMBL) enhanced by antibiotic treatment
Benjamin T. Seiler,Mark Cartwright,Alexandre L. M. Dinis,Shannon C Duffy,Patrick Lombardo,David Cartwright,Elana H. Super,Jacqueline Lanzaro,Kristen Dugas,Michael Super,Donald E. Ingber +10 more
TL;DR: As FcMBL can bind to pathogens and PAMPs in urine as well as blood, its broad-binding capability could be leveraged to develop a variety of clinically relevant technologies, including infectious disease diagnostics, therapeutics, and vaccines.
Journal ArticleDOI
Broad-Spectrum Extracellular Antiviral Properties of Cucurbit[n]urils
Luke M. Jones,Elana H. Super,Lauren J. Batt,Matteo Gasbarri,Benjamin T. Cheesman,Andrew M. Howe,Roger J. Coulston,Samuel T. Jones +7 more
TL;DR: It is demonstrated that CB[7] is the active homologue of CB[n] mixtures, having an antiviral effect against enveloped and non-enveloped species, demonstrating the potential of supramolecular interactions for future antiviral disinfectants.