E
Elie G. Hanania
Publications - 9
Citations - 256
Elie G. Hanania is an academic researcher. The author has contributed to research in topics: Population & Cytometry. The author has an hindex of 5, co-authored 9 publications receiving 245 citations.
Papers
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Journal ArticleDOI
High‐throughput laser‐mediated in situ cell purification with high purity and yield
Manfred R. Koller,Elie G. Hanania,Janine Stevens,Timothy M. Eisfeld,Glenn C. Sasaki,Annabeth Fieck,Bernhard O. Palsson +6 more
TL;DR: This work has shown that existing purification methods are generally open loop and exhibit an inverse relation between cell purity and yield, and this work aims to address that problem.
Journal ArticleDOI
Optoinjection for efficient targeted delivery of a broad range of compounds and macromolecules into diverse cell types
Imran B. Clark,Elie G. Hanania,Janine Stevens,Marijo Gallina,Annabeth Fieck,Rolf Brandes,Bernhard O. Palsson,Manfred R. Koller +7 more
TL;DR: The broad utility of optoinjection is established, and the first to demonstrate its implementation in an automated, high-throughput manner is demonstrated.
Journal ArticleDOI
Automated in situ measurement of cell-specific antibody secretion and laser-mediated purification for rapid cloning of highly-secreting producers.
Elie G. Hanania,Annabeth Fieck,Janine Stevens,Leon J. Bodzin,Bernhard O. Palsson,Manfred R. Koller +5 more
TL;DR: A novel, automated, high-throughput instrument was used to image and locate every cell, quantify the cell-associated and secreted antibody (surrounding each cell), eliminate all undesired cells from a well via targeted laser irradiation, and then track clone outgrowth and stability.
Journal ArticleDOI
Scanning cytometry with a LEAP: Laser‐enabled analysis and processing of live cells in situ
Peter Szaniszlo,William A. Rose,Nan Wang,Lisa M. Reece,Tamara V. Tsulaia,Elie G. Hanania,Cornelis J. Elferink,James F. Leary +7 more
TL;DR: A new technology, called LEAP™ (laser‐enabled analysis and processing), offers a unique combination of capabilities in cell purification and selective macromolecule delivery (optoinjection).
Patent
Method and apparatus for cell permeabilization
TL;DR: In this article, the authors describe a method for transiently permeabilizing a living cell so that any one or more of a variety of substances, such as ions, proteins, and nucleic acids, can be loaded into or released out of the cell.