Elisabet Jerlhag

TL;DR: Findings indicate that ghrelin might, via activation of GHSR‐1A in the VTA and LDTg, stimulate the acetylcholine–dopamine reward link, implicating that gh Relin is a part of the neurochemical overlap between the reward systems and those that regulate energy balance.

TL;DR: Central ghrelin signaling, via GHS-R1A, not only stimulates the reward system, but is also required for stimulation of that system by alcohol.

TL;DR: Ghrelin may, via activation of the acetylcholine–dopamine reward link, increase the incentive values of signals associated with motivated behaviours of importance for survival such as feeding behaviour, and whether this has therapeutic implications for compulsive addictive behaviours.

TL;DR: This article investigated whether ghrelin action at the level of the ventral tegmental area (VTA), a key node in the mesolimbic reward system, is important for the rewarding and motivational aspects of the consumption of rewarding/palatable food.

TL;DR: The central ghrelin signalling system interfaces neurobiological circuits involved in reward from food as well as chemical drugs; agents that directly or indirectly suppress this system emerge as potential candidate drugs for suppressing problematic over-eating that leads to obesity as wellAs for the treatment of substance use disorder.