Elisabetta Mencaroni

TL;DR: Analysis of the literature showed that gut dysbiosis in ASD has been widely demonstrated, but there is no single distinctive profile of the composition of the microbiota in people with ASD, and probiotics are still the most promising treatment for neurobehavioural symptoms and bowel dysfunction.

TL;DR: In this article, the most relevant clinical and pathogenetic issues related to drug-resistant epilepsy were analyzed and the current evidence about the use of available antiseizure medications and the alternative non-pharmacological approaches.

TL;DR: Melatonin can be safe and effective in treating both primary sleep disorders and the sleep disorders associated with various neurological conditions, however, there is a need for further studies aimed at identifying the sleep disordered infants and children who will benefit most from melatonin treatment, and determining appropriate doses based on the severity and type of disorder.

TL;DR: Considering that an early diagnosis and a shorter lag time to treatment are essential for successful outcomes in these patients, further studies on efficacy of the different therapeutic approaches with evaluation of final outcome after cessation of therapy are needed.

TL;DR: It is shown that most children with FS have an excellent prognosis, and few develop long-term health problems, and it is extremely important to improve the knowledge of pediatricians and neurologists on FS management and to standardize the diagnostic and therapeutic work-up.