Showing papers by "Elizabeth Crowne published in 2004"
TL;DR: Time will tell whether the authors are able to change a situation such as this, requiring a focussed and co-operative approach from many organisations, before the children of today become the morbidity and mortality figures of tomorrow.
16 citations
TL;DR: Four cases of fatty liver that occurred acutely after excision of suprasellar tumors are presented and one child developed cirrhosis with portal hypertension, highlighting the need to monitor liver function in patients with supraserpine tumors.
Abstract: Suprasellar tumors of the hypothalamus and pituitary gland, such as craniopharyngiomas, account for approximately 7% of intracranial tumors in childhood (1,2). The usual treatment is neurosurgical excision, and sequelae include pituitary dysfunction and hyperphagia with weight gain. Complications may occur before surgery as a result of the position of the tumor or after neurosurgical excision (2). Fatty liver disease is is now increasingly recognized in developed countries in relation to obesity, insulin resistance and type 2 diabetes mellitus (3). We present four cases of fatty liver that occurred acutely after excision of suprasellar tumors. In all cases, long-term evidence of fatty liver has been observed. One child developed cirrhosis with portal hypertension. This phenomenon has not previously been reported, and it highlights the need to monitor liver function in patients with suprasellar tumors.
9 citations