E
Ellen G. Press
Researcher at University of Pittsburgh
Publications - 29
Citations - 3084
Ellen G. Press is an academic researcher from University of Pittsburgh. The author has contributed to research in topics: Ceftazidime/avibactam & Klebsiella pneumoniae. The author has an hindex of 25, co-authored 29 publications receiving 2483 citations.
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Journal ArticleDOI
Emergence of Ceftazidime-Avibactam Resistance Due to Plasmid-Borne blaKPC-3 Mutations during Treatment of Carbapenem-Resistant Klebsiella pneumoniae Infections.
Ryan K. Shields,Liang Chen,Shaoji Cheng,Kalyan D. Chavda,Ellen G. Press,Avin C. Snyder,Ruchi Pandey,Yohei Doi,Barry N. Kreiswirth,M. Hong Nguyen,Cornelius J. Clancy +10 more
TL;DR: The development of resistance-conferring blaKPC-3 mutations in K. pneumoniae within 10 to 19 days of ceftazidime-avibactam exposure is troubling, but clinical impact may be ameliorated if carbapenem susceptibility is restored in certain isolates.
Journal ArticleDOI
Clinical Outcomes, Drug Toxicity, and Emergence of Ceftazidime-Avibactam Resistance Among Patients Treated for Carbapenem-Resistant Enterobacteriaceae Infections.
Ryan K. Shields,Brian A. Potoski,Ghady Haidar,Binghua Hao,Yohei Doi,Liang Chen,Ellen G. Press,Barry N. Kreiswirth,Cornelius J. Clancy,M. Hong Nguyen +9 more
TL;DR: Thirty-seven carbapenem-resistant Enterobacteriaceae-infected patients treated with ceftazidime-avibactam showed clinical success and survival rates and resistance was detected in 30% (3/10) of microbiologic failures.
Journal ArticleDOI
Ceftazidime-Avibactam Is Superior to Other Treatment Regimens against Carbapenem-Resistant Klebsiella pneumoniae Bacteremia.
Ryan K. Shields,M. Hong Nguyen,Liang Chen,Ellen G. Press,Brian A. Potoski,Rachel V Marini,Yohei Doi,Barry N. Kreiswirth,Cornelius J. Clancy +8 more
TL;DR: There are no data comparing outcomes of patients treated with ceftazidime-avibactam versus comparators for carbapenem-resistant Enterobacteriaceae infections and across treatment groups, there were no differences in underlying diseases, severity of illness, source of bacteremia, or strain characteristics.
Journal ArticleDOI
Performance of Candida Real-time Polymerase Chain Reaction, β-D-Glucan Assay, and Blood Cultures in the Diagnosis of Invasive Candidiasis
M. Hong Nguyen,Mark C. Wissel,Ryan K. Shields,Martin Salomoni,Binghua Hao,Ellen G. Press,Ryan M. Shields,Shaoji Cheng,Dimitra Mitsani,Aniket Vadnerkar,Fernanda P. Silveira,Steven B. Kleiboeker,Cornelius J. Clancy +12 more
TL;DR: Candida PCR and, to a lesser extent, BDG testing significantly enhanced the ability of blood cultures to diagnose IC.
Journal ArticleDOI
Ceftolozane-Tazobactam for the Treatment of Multidrug-Resistant Pseudomonas aeruginosa Infections: Clinical Effectiveness and Evolution of Resistance.
Ghady Haidar,Nathan J Philips,Ryan K. Shields,Daniel J. Snyder,Shaoji Cheng,Brian A. Potoski,Yohei Doi,Binghua Hao,Ellen G. Press,Vaughn S. Cooper,Cornelius J. Clancy,M. Hong Nguyen +11 more
TL;DR: In this small study, ceftolozane-tazobactam was successful in treating 71% of patients with MDR-P.