Machine Learning is the study of methods for programming computers to learn. Computers are applied to a wide range of tasks, and for most of these it is relatively easy for programmers to design and implement the necessary software. However, there are many tasks for which this is difficult or impossible. These can be divided into four general categories. First, there are problems for which there exist no human experts. For example, in modern automated manufacturing facilities, there is a need to predict machine failures before they occur by analyzing sensor readings. Because the machines are new, there are no human experts who can be interviewed by a programmer to provide the knowledge necessary to build a computer system. A machine learning system can study recorded data and subsequent machine failures and learn prediction rules. Second, there are problems where human experts exist, but where they are unable to explain their expertise. This is the case in many perceptual tasks, such as speech recognition, hand-writing recognition, and natural language understanding. Virtually all humans exhibit expert-level abilities on these tasks, but none of them can describe the detailed steps that they follow as they perform them. Fortunately, humans can provide machines with examples of the inputs and correct outputs for these tasks, so machine learning algorithms can learn to map the inputs to the outputs. Third, there are problems where phenomena are changing rapidly. In finance, for example, people would like to predict the future behavior of the stock market, of consumer purchases, or of exchange rates. These behaviors change frequently, so that even if a programmer could construct a good predictive computer program, it would need to be rewritten frequently. A learning program can relieve the programmer of this burden by constantly modifying and tuning a set of learned prediction rules. Fourth, there are applications that need to be customized for each computer user separately. Consider, for example, a program to filter unwanted electronic mail messages. Different users will need different filters. It is unreasonable to expect each user to program his or her own rules, and it is infeasible to provide every user with a software engineer to keep the rules up-to-date. A machine learning system can learn which mail messages the user rejects and maintain the filtering rules automatically. Machine learning addresses many of the same research questions as the fields of statistics, data mining, and psychology, but with differences of emphasis. Statistics focuses on understanding the phenomena that have generated the data, often with the goal of testing different hypotheses about those phenomena. Data mining seeks to find patterns in the data that are understandable by people. Psychological studies of human learning aspire to understand the mechanisms underlying the various learning behaviors exhibited by people (concept learning, skill acquisition, strategy change, etc.).

Machine learning

So far in this course we have dealt entirely with the evolution of characters that are controlled by simple Mendelian inheritance at a single locus. There are notes on the course website about gametic disequilibrium and how allele frequencies change at two loci simultaneously, but we didn’t discuss them. In every example we’ve considered we’ve imagined that we could understand something about evolution by examining the evolution of a single gene. That’s the domain of classical population genetics. For the next few weeks we’re going to be exploring a field that’s actually older than classical population genetics, although the approach we’ll be taking to it involves the use of population genetic machinery. If you know a little about the history of evolutionary biology, you may know that after the rediscovery of Mendel’s work in 1900 there was a heated debate between the “biometricians” (e.g., Galton and Pearson) and the “Mendelians” (e.g., de Vries, Correns, Bateson, and Morgan). Biometricians asserted that the really important variation in evolution didn’t follow Mendelian rules. Height, weight, skin color, and similar traits seemed to

Human biochemical genetics

Today’s artificial intelligence still faces two major challenges. One is that, in most industries, data exists in the form of isolated islands. The other is the strengthening of data privacy and security. We propose a possible solution to these challenges: secure federated learning. Beyond the federated-learning framework first proposed by Google in 2016, we introduce a comprehensive secure federated-learning framework, which includes horizontal federated learning, vertical federated learning, and federated transfer learning. We provide definitions, architectures, and applications for the federated-learning framework, and provide a comprehensive survey of existing works on this subject. In addition, we propose building data networks among organizations based on federated mechanisms as an effective solution to allowing knowledge to be shared without compromising user privacy.

Federated Machine Learning: Concept and Applications

Mash extends the MinHash dimensionality-reduction technique to include a pairwise mutation distance and P value significance test, enabling the efficient clustering and search of massive sequence collections. Mash reduces large sequences and sequence sets to small, representative sketches, from which global mutation distances can be rapidly estimated. We demonstrate several use cases, including the clustering of all 54,118 NCBI RefSeq genomes in 33 CPU h; real-time database search using assembled or unassembled Illumina, Pacific Biosciences, and Oxford Nanopore data; and the scalable clustering of hundreds of metagenomic samples by composition. Mash is freely released under a BSD license (
 https://github.com/marbl/mash
 ).

/pdf/mash-fast-genome-and-metagenome-distance-estimation-using-3b84vfnedh.pdf

Mash: fast genome and metagenome distance estimation using MinHash.

Today's AI still faces two major challenges. One is that in most industries, data exists in the form of isolated islands. The other is the strengthening of data privacy and security. We propose a possible solution to these challenges: secure federated learning. Beyond the federated learning framework first proposed by Google in 2016, we introduce a comprehensive secure federated learning framework, which includes horizontal federated learning, vertical federated learning and federated transfer learning. We provide definitions, architectures and applications for the federated learning framework, and provide a comprehensive survey of existing works on this subject. In addition, we propose building data networks among organizations based on federated mechanisms as an effective solution to allow knowledge to be shared without compromising user privacy.

The increasing reliance on online social networks for user engagement motivates the need to understand and counter reputation manipulation activities, such as boosting the number of likes of a Facebook page. This paper presents an in-depth analysis of Facebook accounts used by a few Like Farms. We crawl their timelines and compare their activities to a baseline sample of normal users. Then, we retrieve the pages they like and cluster their activity. We find that, compared to normal users, posts from Like Farms' accounts often consist of re-shared content, have fewer words and poor vocabulary, are targeted to a limited number of topics and generate more comments and likes. Profiles used by Like Farms are also more likely to be tagged or tag their friends and their likes are concentrated toward specific pages. While we highlight the difficulty of currently deployed anti-fraud tools to detect stealthy behavior, our analysis provides important insights that can be incorporated in clustering algorithms to detect Like Farms networks.

Spying on Spammers: Tracking Like Farm Accounts on Facebook.

This paper presents a multi-platform computational pipeline geared to identify social media posts discussing (known) conspiracy theories. We use 189 conspiracy claims collected by Snopes, and find 66k posts and 277k comments on Reddit, and 379k tweets discussing them. Then, we study how conspiracies are discussed on different Web communities and which ones are particularly influential in driving the discussion about them. Our analysis sheds light on how conspiracy theories are discussed and spread online, while highlighting multiple challenges in mitigating them.

Emiliano De Cristofaro

Papers

Spying on Spammers: Tracking Like Farm Accounts on Facebook.

Soros, Child Sacrifices, and 5G: Understanding the Spread of Conspiracy Theories on Web Communities.