Emily F. Collier

TL;DR: This study demonstrates the applicability of custom-focused microarray technology in addressing hypothesis-driven questions regarding the action of antidepressants by examining the expression of other neurotrophic-growth factors and related signaling pathways in the hippocampus in response to ECS using a custom growth factor microarray chip.

TL;DR: Increasing mitochondrial uncoupling in skeletal muscle may be an excellent therapeutic target for type 2 diabetes mellitus by protecting against fat-induced insulin resistance in muscle by conversion of intramyocellular fat into thermal energy.

TL;DR: The SLM of the hippocampus exhibited a robust 20–30% increase in vascular density and was accompanied by an increase in expression of inhibitor of differentiation‐3, which could be in response to enhanced metabolic activity in this region.

TL;DR: In situ hybridization analysis revealed a more than 2-fold induction of Grb2 mRNA in the hippocampal dentate gyrus as well as superficial and deep layers of the cortex with both acute and chronic ECS, providing further evidence of increased growth factor signaling in response to ECS.

TL;DR: Electroconvulsive seizure-induced remodelling occurs at the vascular basement membrane and facilitates neovascularization, and the expression of TIMP-1 mRNA in relation to vasculature in the SLM and glial-limiting membrane is characterized.