E
Enping Xu
Researcher at Zhejiang University
Publications - 49
Citations - 2315
Enping Xu is an academic researcher from Zhejiang University. The author has contributed to research in topics: Colorectal cancer & Cancer. The author has an hindex of 23, co-authored 45 publications receiving 1896 citations. Previous affiliations of Enping Xu include Sir Run Run Shaw Hospital & University of Texas MD Anderson Cancer Center.
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Epithelial–mesenchymal transition in colorectal cancer metastasis: A system review
TL;DR: This work focuses on the molecular network of the EMT program and its malignant phenotypes associated with metastasis in colorectal cancer (CRC), including cancer stem cells, tumor budding, circulating tumor cells and drug resistance.
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Mutations of key driver genes in colorectal cancer progression and metastasis
Dongdong Huang,Wenjie Sun,Yuwei Zhou,Peiwei Li,Fang Chen,Hanwen Chen,Dajing Xia,Enping Xu,Maode Lai,Yihua Wu,Honghe Zhang +10 more
TL;DR: A comprehensive analysis to screen key driver genes from the TCGA database and validate the roles of these mutations in CRC metastasis found mutations of KRAS, p53, SMAD4 and BRAF play significant roles in CRC cancer metastasis and may be both potential biomarkers of CRC metastases as well as therapeutic targets.
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Long non-coding RNA LINC01133 inhibits epithelial-mesenchymal transition and metastasis in colorectal cancer by interacting with SRSF6.
Jianlu Kong,Wenjie Sun,Chen Li,Ledong Wan,Shuo Wang,Yihua Wu,Enping Xu,Honghe Zhang,Maode Lai +8 more
TL;DR: The data suggest that LINC01133 inhibits the EMT and metastasis by directly binding to SRSF6 as a target mimic, and may serve as a prognostic biomarker and an effective target for anti-metastasis therapies for CRC.
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Overexpression of glucose-regulated protein 78 in colon cancer.
TL;DR: The findings indicate that overexpression ofGRP78 protein may be an important biomarker for malignant transformation, and increased expression might be related with the posttranscriptional regulation of GRP78 in tumor tissues.
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MiR-22 regulates 5-FU sensitivity by inhibiting autophagy and promoting apoptosis in colorectal cancer cells
TL;DR: It is shown that miR-22 inhibited autophagy and promoted apoptosis to increase the sensitivity of colorectal cancer cells to 5-fluorouracil (5-FU) treatment both in vitro and in vivo.