E
Eric G. Brown
Researcher at Swansea University
Publications - 42
Citations - 815
Eric G. Brown is an academic researcher from Swansea University. The author has contributed to research in topics: Cyclic nucleotide phosphodiesterase & Phosphodiesterase. The author has an hindex of 16, co-authored 42 publications receiving 804 citations. Previous affiliations of Eric G. Brown include University of Siena.
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Journal ArticleDOI
Cyclic AMP and higher plants
Eric G. Brown,Russell P. Newton +1 more
TL;DR: Evidence of 3′: 5′-cyclic nucleotide phosphodiesterases in higher plants, together with adenylate cyclase, a specific cyclic AMP binding protein, and calmodulin means that plants possess all the necessary components for a functional cyclicAMP-regulated system.
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Analysis of the free nucleotide pools of mammalian tissues by high-pressure liquid chromatography
TL;DR: A high-pressure liquid chromatographic anion-exchange procedure was developed and gave good resolution of the naturally occurring free nucleotides on a single column, and both reverse-phase and paired-ion chromatography gave excellent separation of cyclic nucleotide.
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Occurrence of guanosine 3′,5′-cyclic monophosphate (Cyclic GMP) and associated enzyme systems in Phaseolus vulgaris
TL;DR: Cyclic GMP, isolated from Phaseolus vulgaris, has been unequivocally identified by NMR and FAB-mass spectrometry with MIKES-scanning as mentioned in this paper.
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Occurrence of adenosine 3′:5′-cyclic monophosphate in plant tissues
Eric G. Brown,Russel P. Newton +1 more
TL;DR: A procedure is described which unequivocally demonstrates the presence of adenosine 3′:5′-cyclic monophosphate in Phaseolus vulgaris.
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Cyclic nucleotide phosphodiesterase activity in Phaseolus vulgaris
TL;DR: The authors showed that 70% of the cyclic nucleotide phosphodiesterase activity of Phaseolus vulgaris seedlings is recovered in the centrifugal fractionation process.