E
Eskil Hansson
Researcher at Astra
Publications - 5
Citations - 395
Eskil Hansson is an academic researcher from Astra. The author has contributed to research in topics: Excretion & Acute toxicity. The author has an hindex of 5, co-authored 5 publications receiving 392 citations.
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Toxicological studies on omeprazole.
TL;DR: The reproduction studies performed in rats and rabbits showed no sign of fetal toxicity or teratogenic effect, and the results of the short-term mutagenicity tests, Ames test, the micronucleus test in mice and the mouse lymphoma test were all negative.
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Toxicology Studies with Omeprazole
TL;DR: A number of toxicological studies in animals have been performed in order to evaluate the safety of omeprazole, and the most important findings are presented.
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Biliary excretion of quaternary ammonium compounds and tertiary amines in the rat.
Åke Ryrfeldt,Eskil Hansson +1 more
TL;DR: The biliary excretion of some isotopically labelled quaternary ammonium compounds and tertiary amines have been studied in rats after intravenous administration and Chromatographic studies indicated that only a small fraction of the activity eliminated into the bile was attributable to the original compound in most of the cases.
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Biliary excretion of ampicillin, azidocillin and benzylpenicillin in the rat.
TL;DR: It is suggested that the high hydrophobic character of the side chain of penicillins (high protein binding) may predispose to extensive biotransformation and lower amounts of unchanged penicillin in the bile.
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Renal lesions induced by alpha-methyltyrosine methylester and alpha-methyltyrosine.
TL;DR: The toxicity of α-methyltyrosine methylester (H 44/68) and α -methyl tyrosine (H 9/88) in the rat was investigated in a four week subacute study as discussed by the authors.