E
Eugene Bosmans
Researcher at University of Antwerp
Publications - 105
Citations - 10699
Eugene Bosmans is an academic researcher from University of Antwerp. The author has contributed to research in topics: Sperm & Proinflammatory cytokine. The author has an hindex of 54, co-authored 102 publications receiving 10087 citations.
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Journal ArticleDOI
The effects of psychological stress on humans: increased production of pro-inflammatory cytokines and a Th1-like response in stress-induced anxiety
Michael Maes,Cai Song,Aihua Lin,Raf De Jongh,An Van Gastel,Gunter Kenis,Eugene Bosmans,Ingrid De Meester,Ina Benoy,Hugo Neels,P. Demedts,Aleksandar Janca,Simon Scharpé,R.S. Smith +13 more
TL;DR: It is suggested that changes in the production of the pro-inflammatory cytokines, TNF-alpha, IL-6 and IFN-gamma, and negative immunoregulatory cytokine,IL-10 and IL-4, take part in the homeostatic responses to psychological stress and that stress-induced anxiety is related to a T-helper-1-like response.
Journal ArticleDOI
Increased plasma concentrations of interleukin-6, soluble interleukin-6, soluble interleukin-2 and transferrin receptor in major depression
Michael Maes,Herbert Y. Meltzer,Eugene Bosmans,Raf Bergmans,Eric Vandoolaeghe,Rakesh Ranjan,Roger Desnyder +6 more
TL;DR: It is suggested that a coordinated and upregulated production of IL-6, sil-6R, sIL-2R and TfR may constitute a trait marker of major depression; and an up regulated production ofIL-6 may represent a contributing factor to the various immune disorders encountered in major depression and maybe to the pathophysiology or pathogenesis of that illness.
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Relationships between interleukin-6 activity, acute phase proteins, and function of the hypothalamic-pituitary-adrenal axis in severe depression.
Michael Maes,Simon Scharpé,Herbert Y. Meltzer,Eugene Bosmans,Eduard Suy,Joseph R. Calabrese,Paul Cosyns +6 more
TL;DR: Investigating whether severe depression is characterized by increased interleukin-6 (Il-6) activity and whether Il-6 production is related to altered levels of acute phase reactants and to abnormal function of the hypothalamic-pituitary-adrenal (HPA) axis found significant and positive correlations between Il- 6 activity and postdexamethasone cortisol values.
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Interleukin-2 and interleukin-6 in schizophrenia and mania: Effects of neuroleptics and mood stabilizers
TL;DR: It is suggested that activation of CMI may occur in both schizophrenia and mania and that neuroleptics may have immunosuppressive effects through suppression of IL- 6 or IL-6R-related mechanisms.
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Indicators of immune activation in major depression
A. Sluzewska,Janusz K. Rybakowski,Eugene Bosmans,Magdalena Sobieska,Robert Berghmans,Michael Maes,Krzysztof Wiktorowicz +6 more
TL;DR: The correlations between cytokines and acute phase proteins studied point to a significant role of elevated IL-6 secretion in the induction of Type I AGP microheterogeneity changes that are characteristic of some inflammatory conditions.