E
Eva-María Priego
Researcher at Spanish National Research Council
Publications - 33
Citations - 734
Eva-María Priego is an academic researcher from Spanish National Research Council. The author has contributed to research in topics: Tubulin & Nucleoside. The author has an hindex of 14, co-authored 31 publications receiving 609 citations. Previous affiliations of Eva-María Priego include Katholieke Universiteit Leuven.
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Journal ArticleDOI
Blocking Blood Flow to Solid Tumors by Destabilizing Tubulin: An Approach to Targeting Tumor Growth
María-Jesús Pérez-Pérez,Eva-María Priego,Oskía Bueno,Maria Solange Martins,María-Dolores Canela,Sandra Liekens +5 more
TL;DR: This Perspective illustrates the different classes of compounds that behave similar to CA-4, analyzes their binding mode to αβ-tubulin according to recently available structural complexes, and includes described approaches to improve their delivery.
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Identification of [1,2,3]triazolo[4,5-d]pyrimidin-7(6H)-ones as novel inhibitors of Chikungunya virus replication.
Alba Gigante,María-Dolores Canela,Leen Delang,Eva-María Priego,María-José Camarasa,Gilles Querat,Johan Neyts,Pieter Leyssen,María-Jesús Pérez-Pérez +8 more
TL;DR: A new family of compounds named [1,2,3]triazolo[4,5-d]pyrimidin-7(6H)-ones that inhibit CHIKV replication in the low micromolar range with no toxicity to the host (Vero) cells are reported on.
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Pyrido[2,1-f]purine-2,4-dione derivatives as a novel class of highly potent human A(3) adenosine receptor antagonists.
Eva-María Priego,Jacobien Von Frijtag Drabbe Kuenzel,Ad P. Ijzerman,María-José Camarasa,María-Jesús Pérez-Pérez +4 more
TL;DR: The described pyrido[2,1-f]purine-2,4-dione derivatives represent a new family of adenosine receptor antagonists which deserves further exploration.
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Thymidine Phosphorylase Inhibitors: Recent Developments and Potential Therapeutic Applications
María-Jesús Pérez-Pérez,Eva-María Priego,Ana-Isabel Hernández,María-José Camarasa,Jan Balzarini,Sandra Liekens +5 more
TL;DR: The most recent approaches in the search for novel TPase inhibitors together with the potential therapeutic applications of such inhibitors are summarized.
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Antiviral activity of [1,2,3]triazolo[4,5-d]pyrimidin-7(6H)-ones against chikungunya virus targeting the viral capping nsP1
Alba Gigante,Asier Gómez-SanJuan,Leen Delang,Changqing Li,Oskía Bueno,Ana-María Gamo,Eva-María Priego,María-José Camarasa,Dirk Jochmans,Pieter Leyssen,Etienne Decroly,Bruno Coutard,Gilles Querat,Johan Neyts,María-Jesús Pérez-Pérez +14 more
TL;DR: The data obtained seem to indicate that the anti‐CHIKV activity might be related to the inhibition of this crucial step in the viral RNA capping machinery, as determined by Western blot using an anti‐cap antibody.