F
F Plata
Publications - 5
Citations - 583
F Plata is an academic researcher. The author has contributed to research in topics: Cytotoxic T cell & CTL*. The author has an hindex of 5, co-authored 5 publications receiving 581 citations.
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Journal Article
Unusually high frequencies of HIV-specific cytotoxic T lymphocytes in humans.
Agnès Hoffenbach,P. Langlade-Demoyen,Gilles Dadaglio,E Vilmer,Frédérique Michel,C Mayaud,Brigitte Autran,F Plata +7 more
TL;DR: Most surprisingly, PBL from seronegative donors also responded to HIV stimulation in vitro and generated large numbers of HLA-restricted, HIV-specific CTL.
Journal Article
Cell-mediated suppression of HIV-specific cytotoxic T lymphocytes.
TL;DR: A progressive decline of alveolar anti-HIV CTL activity is demonstrated and Ts cells from the lungs of patients with advanced HIV disease are detected and could partly explain the inefficiency of host defenses against HIV.
Journal Article
Epitope recognition of conserved HIV envelope sequences by human cytotoxic T lymphocytes.
Gilles Dadaglio,A. Leroux,P. Langlade-Demoyen,El Mostapha Bahraoui,F. Traincard,R. Fisher,F Plata +6 more
TL;DR: Using synthetic peptides, this study has identified six conserved peptidic epitopes on the gp120 envelope glycoprotein recognized by polyclonal human CTL in association with HLA-A2 class I transplantation Ag.
Journal ArticleDOI
Increased lung epithelial permeability in HIV-infected patients with isolated cytotoxic T-lymphocytic alveolitis
Michel Meignan,J. M. Guillon,M. Denis,P Joly,Jean Rosso,M F Carette,L. Baud,F Parquin,F Plata,Patrice Debré +9 more
TL;DR: Results suggest that an injury of the lung epithelium could result from a HIV-specific CTL-induced immunologic conflict.
Journal Article
Immune recognition of AIDS virus antigens by human and murine cytotoxic T lymphocytes.
Pierre Langlade-Demoyen,Frédérique Michel,Agnès Hoffenbach,E Vilmer,Gilles Dadaglio,F Garicia-Pons,C Mayaud,Brigitte Autran,S Wain-Hobson,F Plata +9 more
TL;DR: Two different experimental systems presented here can be used to study CD8 lymphocyte immunity against HIV: the murine model of CTL immunity offers the additional advantage of avoiding the manipulation of infectious virus isolates and the novel and strictly autologous lymphocyte culture system.