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Fang Han

Researcher at Weifang Medical University

Publications -  51
Citations -  912

Fang Han is an academic researcher from Weifang Medical University. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 15, co-authored 30 publications receiving 527 citations. Previous affiliations of Fang Han include University of Mississippi Medical Center.

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Calycosin directly improves perivascular adipose tissue dysfunction by upregulating the adiponectin/AMPK/eNOS pathway in obese mice

TL;DR: It is indicated that calycosin restored PVAT induced anti-contractile activity and affected PVAT function through the adiponectin/AMPK/eNOS pathway in obese mice.
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Protective effects of adiponectin on uncoupling of glomerular VEGF-NO axis in early streptozotocin-induced type 2 diabetic rats.

TL;DR: Adiponectin reduces the degree of microalbuminuria and has renal protective effects by improving endothelial dysfunction and uncoupling of the glomerular VEGF–NO axis in early diabetic nephropathy.
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Liraglutide improves obesity-induced renal injury by alleviating uncoupling of the glomerular VEGF-NO axis in obese mice.

TL;DR: Liraglutide reduced microalbuminuria and ameliorated renal injury by alleviating the uncoupling of the glomerular VEGF–NO axis and activated the glomersular AMPK–eNOS pathway in obesity mice, upregulated renal haeme oxygenase‐1 activity, and reduced the renal malondialdehyde levels in obese mice.
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Renal protective effects of induction of haem oxygenase-1 combined with increased adiponectin on the glomerular vascular endothelial growth factor-nitric oxide axis in obese rats.

TL;DR: In this paper, the authors investigated whether HO-1 can protect the kidneys of obese rats by regulating the glomerular vascular endothelial growth factor-nitric oxide (VEGF)-NO axis by increasing the adiponectin concentrations.
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Growth differentiation factor 11: a "rejuvenation factor" involved in regulation of age-related diseases?

TL;DR: Growth differentiation factor 11 (GDF11), a member of the transforming growth factor β superfamily of cytokines, is a critical rejuvenation factor in aging cells as discussed by the authors, which improves neurodegenerative and neurovascular disease outcomes, increases skeletal muscle volume, and enhances muscle strength.