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Farha Naaz

Researcher at Allahabad University

Publications -  11
Citations -  194

Farha Naaz is an academic researcher from Allahabad University. The author has contributed to research in topics: Docking (molecular) & Antibacterial activity. The author has an hindex of 4, co-authored 11 publications receiving 84 citations.

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Molecular modeling, synthesis, antibacterial and cytotoxicity evaluation of sulfonamide derivatives of benzimidazole, indazole, benzothiazole and thiazole

TL;DR: A new series of heterocyclic molecules bearing sulfonamide linkage has been synthesized and screened for antibacterial activity and positively indicated towards the development of lead antibacterials using the combination approach.
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Anti-HIV potential of diarylpyrimidine derivatives as non-nucleoside reverse transcriptase inhibitors: design, synthesis, docking, TOPKAT analysis and molecular dynamics simulations.

TL;DR: The designed diarylpyrimidine derivatives have shown promising docking results, which revealed that all compounds formed hydrogen bonds with Lys101, Lys103, Tyr 181, Tyr318 and π- interactions with Tyr181, Tyr188, Phe227 and Trp229 amino acid residues located in the non-nucleoside inhibitor binding pocket of HIV-RT protein.
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Synthesis, antibacterial activity, synergistic effect, cytotoxicity, docking and molecular dynamics of benzimidazole analogues.

TL;DR: In-vitro cytotoxicity study indicated that 2-Cl-benzimidazole derivatives showed less toxicity than the reference used against PBM, CEM and Vero cell lines.
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Alkylated benzimidazoles: Design, synthesis, docking, DFT analysis, ADMET property, molecular dynamics and activity against HIV and YFV.

TL;DR: A series of alkylated benzimidazole derivatives was synthesized and screened for their anti-HIV, anti-YFV, and broad-spectrum antiviral properties and indicated that the molecules behaved like possible NNRTIs.
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Molecular modeling, QSAR analysis and antimicrobial properties of Schiff base derivatives of isatin

TL;DR: The study laid the foundation for the development of better antibacterial agents via a combination approach and safe agricultural fungicides through in vitro antimicrobial activity of a new series of novel Schiff bases.