Showing papers by "Fernando Martínez-Martínez published in 2008"

Application of the SCORE and Wilson–Grundy methods for the assessment of cardiovascular risk in community pharmacies

Abstract: Background: The assessment and follow-up of patients with risk factors, or with cardiovascular disease (CVD), involves estimating and monitoring their CVD risk (CVDR). There are different opinions about the most appropriate method for this. Objective: To compare the SCORE system and the Wilson-Grundy system (based on Framingham's study). Methods: A descriptive, observational study over 15 days in six pharmacies, with patients aged between 25 and 74 years, and with a prescription for medications related to hypertension, dyslipidaemia, CVD prevention or type-2 diabetes. Results of patients' absolute CVDR were assessed and compared using the SCORE system and the Wilson-Grundy method, adapted for Spain. The Chi-square test was used to compare proportions, and the Student t-test was used to compare mean values, including odds ratios (OR) and 95% confidence intervals (95%CI). Result: A total of 257 patients [165 women, 92 men; mean (SD) age, 60-9 (10-8) years; percentage of previous medical history of hypertension (70-0%), dyslipidaemia (42.4%), type-2 diabetes (19-5%) and CVD (22.6%)] participated. With the Received 15 June 2006, Accepted 25 November 2007 Correspondence: P. Amariles, Faculty of Pharmaceutical Chemist, University of Antioquia, AA 1226 Medellin, Colombia. Tel.: +574 2195460; fax: +574 2195456; e-mail: pamaris@farma cia.udea.edu.co CVDR assessed with SCORE, the distribution was as follows: low 35-8%, intermediate 21-0% and high 43-2%. The corresponding values using the Wilson-Grundy system was low 60-7%, intermediate 8-2% and high 31-1%. Conclusion: The cardiovascular risk of patients that attend community pharmacies with prescriptions for cardiovascular medications is significantly higher when assessed using the SCORE system than with the Wilson-Grundy method.