Ferran Guedea

TL;DR: Recommendations will provide clinical guidance regarding the use of APBI outside the context of a clinical trial before large-scale randomized clinical trial outcome data become available and should promote further clinical research focusing on controversial issues in the treatment of early-stage breast carcinoma.

TL;DR: Relevant differences between treatment groups persisted for up to 3 years of follow- up, although the difference in sexual adverse effects between brachytherapy and prostatectomy tended to decline over long-term follow-up.

TL;DR: The non-inferiority of accelerated partial breast irradiation with interstitial brachytherapy in terms of local control and overall survival compared with whole-breast irradiation for patients with early-stage breast cancer who underwent breast-conserving surgery in a phase 3 randomised trial is confirmed.

TL;DR: Relevant differences between treatment groups persisted after 2 years of follow-up, and radical prostatectomy had a considerable negative effect on sexual functioning and urinary continence, and three-dimensional conformal radiotherapy had a moderate negative impact on bowel functioning and brachytherapy caused moderate urinary irritation.

TL;DR: In this paper, the authors performed a prospective analysis of local tumor control, survival and treatment complications in 67 consecutive patients treated with fractionated photon and proton radiation for chordoma or chondrosarcoma of the base of the skull and the cervical spine.