F
Filomena Cariola
Publications - 21
Citations - 403
Filomena Cariola is an academic researcher. The author has contributed to research in topics: Familial adenomatous polyposis & Germline mutation. The author has an hindex of 10, co-authored 19 publications receiving 370 citations.
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Journal ArticleDOI
Involvement of PTEN mutations in the genetic pathways of colorectal cancerogenesis
Ginevra Guanti,Nicoletta Resta,Cristiano Simone,Filomena Cariola,Ignazio Demma,Paola Fiorente,Mattia Gentile +6 more
TL;DR: The mutation of both PTEN alleles and evidence that the PTEN protein is expressed in normal colon suggest that loss of function of this gene could play a direct role in tumorigenesis.
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PD-L1 expression in colorectal cancer defines three subsets of tumor immune microenvironments.
Anna Maria Valentini,Federica Di Pinto,Filomena Cariola,Vito Guerra,Gianluigi Giannelli,Maria Lucia Caruso,M. Pirrelli +6 more
TL;DR: The study calls attention to the importance to assess PD-L1 expression in tumor microenvironment also evaluating type and density of infiltrating immune cells to better stratify CRCs with different immunological patterns.
Journal ArticleDOI
Identification of two new mutations in TRPS 1 gene leading to the tricho‐rhino‐phalangeal syndrome type I and III
Maria Piccione,Marcello Niceta,Vincenzo Antona,Antonella Di Fiore,Filomena Cariola,Mattia Gentile,Giovanni Corsello +6 more
TL;DR: Identification of Two New Mutations in TRPS 1 Gene Leading to the Tricho-Rhino-Phalangeal Syndrome Type I and III is identified.
Journal ArticleDOI
Low presence of p53 abnormalities in H pylori-infected gastric mucosa and in gastric adenocarcinoma.
Pasquale Berloco,Francesco Russo,Filomena Cariola,Mattia Gentile,Piero Giorgio,Maria Lucia Caruso,Anna Maria Valentini,Giovanni Di Matteo,Alfredo Di Leo +8 more
TL;DR: It is hypothesized that H. pylori infection does not affect the p53 pattern in gastric mucosa, at least in populations of patients with dyspepsia and with gastric cancer.
Journal ArticleDOI
Oestrogen receptors and microsatellite instability in colorectal carcinoma patients
Maria Notarnicola,Roberto Gristina,Caterina Messa,Filomena Cariola,Paola Fiorente,Maria Lucia Caruso,Mattia Gentile,Alfredo Di Leo +7 more
TL;DR: The findings suggest that MIN-positive tumours might lose a possible oestrogenic modulation mechanism, and microsatellite instability in sporadic colorectal cancers may be a mutator phenotype of mismatch repair genes.