F
Francesca Svetoni
Researcher at Sapienza University of Rome
Publications - 4
Citations - 126
Francesca Svetoni is an academic researcher from Sapienza University of Rome. The author has contributed to research in topics: Alternative splicing & Exon. The author has an hindex of 3, co-authored 3 publications receiving 97 citations.
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Journal ArticleDOI
Role of FET proteins in neurodegenerative disorders
TL;DR: Recent works documenting the involvement of FET proteins in the pathology of ALS, FTLD, essential tremor (ET) and other neurodegenerative diseases are summarized and clinical implications of recent advances in FET research are critically discussed.
Journal ArticleDOI
Genotoxic stress inhibits Ewing sarcoma cell growth by modulating alternative pre-mRNA processing of the RNA helicase DHX9
Marco Fidaleo,Francesca Svetoni,Elisabetta Volpe,Belén Miñana,Daniela Caporossi,Maria Paola Paronetto +5 more
TL;DR: RNA profiling reveals genes differentially regulated by UV light irradiation in two ES cell lines exhibiting different sensitivity to genotoxic stress, and identifies a new NMD-linked splicing event in DHX9 with impact on EWS-FLI1 oncogenic activity and ES cell viability.
Journal ArticleDOI
Post-transcriptional regulation of FUS and EWS protein expression by miR-141 during neural differentiation.
Francesca Svetoni,Elisa De Paola,Piergiorgio La Rosa,Neri Mercatelli,Daniela Caporossi,Claudio Sette,Maria Paola Paronetto +6 more
TL;DR: This study identifies a fine-tuned regulation of FUS and EWS during neuronal differentiation, whereas TAF15 appears to be more constitutively expressed, and identifies miR-141 as a key regulator of these FET proteins that modulate their expression levels in differentiating neuronal cells.
Journal ArticleDOI
EWS splicing regulation contributes to balancing Foxp1 isoforms required for neuronal differentiation
Veronica Verdile,Francesca Svetoni,Piergiorgio La Rosa,Gabriele Ferrante,Eleonora Cesari,Claudio Sette,Maria Paola Paronetto +6 more
TL;DR: It is found that the Ewing sarcoma protein (EWS) controls the alternative splicing of the forkhead family transcription factor FOXP1, a pivotal transcriptional regulator of neuronal differentiation, possibly contributing to the switch of gene expression underlying the neuronal differentiation program.