F
François Bernard
Publications - 1
Citations - 34
François Bernard is an academic researcher. The author has contributed to research in topics: Drug design & Enzyme structure. The author has an hindex of 1, co-authored 1 publications receiving 29 citations.
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Design of potent IGF1-R inhibitors related to bis-azaindoles.
Conception Nemecek,William A. Metz,Sylvie Wentzler,Ding Fa-Xiang,Corinne Venot,Catherine Souaille,Anne Dagallier,Sébastien Maignan,Jean-Pierre Guilloteau,François Bernard,Alain Henry,Sandrine Grapinet,Dominique Lesuisse +12 more
TL;DR: A series of potent bis‐azaindole inhibitors of IGF1‐R have been synthesized using rational drug design and SAR based on a in silico binding mode hypothesis, but the model was not validated by the co‐crystallization experiments with IGF 1‐R.