Many techniques are available in the fermentation medium designer’s toolbox (borrowing, component swapping, biological mimicry, one-at-a-time, statistical and mathematical techniques—experimental design and optimization, artificial neural networks, fuzzy logic, genetic algorithms, continuous fermentation, pulsed batch and stoichiometric analysis). Each technique has advantages and disadvantages, and situations where they are best applied. No one ‘magic bullet’ technique exists for all situations. However, considerable advantage can be gained by logical application of the techniques, combined with good experimental design.

Strategies for improving fermentation medium performance: a review

Biotechnology development in India: Some policy issues☆

By nurturing yeast cultures in alcohols or sugars instead of gas-oil or n-paraffins, this biosynthetic route produces single-cell protein products at ultrahigh cell densities, eliminating the need for handling waste or recycle streams

G. H. Wegner

Papers

Nonpolluting process turns methanol into pure protein