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Showing papers by "Gabriel Rubio published in 2013"


Journal ArticleDOI
TL;DR: Results show that pathological gamblers, but not healthy volunteers, had attentional bias for gambling-related cues with exposure times that assess maintenance of attention, and the correlation between PG severity and degree of Attentional bias among individuals with PG was examined.
Abstract: In the study of addiction, attentional bias refers to the observation that substance-related cues tend tocapture the attention of experienced substance users. Attentional bias is a cognitive intermediate in theconditioned association between drug-related cues, craving, and relapse. Numerous studies have docu-mentedtheexistenceofattentionalbiasforcuesassociatedwithsubstances.Bycontrast,fewstudieshaveinvestigated attentional bias in individuals with pathological gambling (PG) or problematic gambling. Inthis study, we sought to assess attentional bias at the level of maintenance of attention in a sample ofpathological gamblers. Twenty-three pathological gamblers and 21 healthy volunteers performed theVisual Probe Task to compare attentional bias with gambling-related cues between individuals with PGand healthy volunteers. The measured of attentional bias was based on their reaction times (RTs) toprobes replacing neutral and gambling-related cues (images). Second, we examined the correlationbetween PG severity and degree of attentional bias among individuals with PG. Results show thatpathological gamblers, but not healthy volunteers, had attentional bias for gambling-related cues withexposure times that assess maintenance of attention. There was no correlation between PG severity anddegree of attentional bias. Theoretical and clinical implications of these results are discussed.

26 citations


Journal ArticleDOI
TL;DR: The publications on SGAs in South Korea have undergone exponential growth over the studied period, without evidence of reaching a saturation point, and fulfilment of fulfilled Price's law is stated.
Abstract: OBJECTIVE We have carried out a bibliometric study on the scientific publications in relation to atypical or second-generation antipsychotic drugs (SGAs) in South Korea. METHODS With the EMBASE and MEDLINE databases, we selected those publications made in South Korea whose title included the descriptors atypic(*) (atypical(*)) antipsychotic(*), second-generation antipsychotic(*), clozapine, risperidone, olanzapine, ziprasidone, quetiapine, sertindole, aripiprazole, paliperidone, amisulpride, zotepine, asenapine, iloperidone, lurasidone, perospirone and blonanserin. We applied some bibliometric indicators of paper production and dispersion with Price's law and Bradford's law, respectively. We also calculated the participation index (PI) of the different countries, and correlated the bibliometric data with some social and health data from Korea (such as total per capita expenditure on health and gross domestic expenditure on research and development). RESULTS We collected 326 original papers published between 1993 and 2011. Our results state fulfilment of fulfilled Price's law, with scientific production on SGAs showing exponential growth (correlation coefficient r=0.8978, as against an r=0.8149 after linear adjustment). The most widely studied drugs were risperidone (91 papers), aripiprazole (77), olanzapine (53), and clozapine (43). Division into Bradford zones yielded a nucleus occupied by the Progress in Neuro-Psychopharmacology and Biological Psychiatry (36 articles). A total of 86 different journals were published, with 4 of the first 10 used journals having an impact factor being greater than 4. CONCLUSION The publications on SGAs in South Korea have undergone exponential growth over the studied period, without evidence of reaching a saturation point.

23 citations


Journal Article
TL;DR: The publications on atypical antipsychotic drugs in Spain have undergone exponential growth over the studied period, without evidence of reaching a saturation point.
Abstract: Objetivos: Se llevo a cabo un estudio bibliometrico de las publicaciones sobre farmacos antipsicoticos atipicos (AA) realizadas en Espana. Metodo: Se usaron las bases de datos EMBASE y MEDLINE y se aplicaron indicadores bibliometricos de productividad y dispersion de articulos (leyes de Price y de Bradford, respectivamente). Tambien se calculo el indice de participacion (IP) de los diferentes paises y se buscaron correlaciones entre los datos bibliometricos y algunos datos sociales y de salud (gasto total per capita en salud y gasto interior bruto en investigacion y desarrollo). Resultados: Se recopilaron 656 articulos originales publicados entre 1988 y 2011. Nuestros resultados constatan el cumplimiento de la ley de Price en la produccion cientifica sobre AA, mostrando un crecimiento exponencial (coeficiente de correlacion r= 0,9693 vs. r= 0,9177 despues del ajuste lineal). Los farmacos mas estudiados fueron la risperidona (181 articulos), la olanzapina (143), la clozapina (94) y la quetiapina (74). La division en zonas de Bradford dio lugar a un nucleo ocupado por las revistas European Psychiatry y European Neuropsychopharmacology (70 articulos). En total se publicaron articulos en 194 revistas diferentes, de las cuales 5 de las 10 primeras tenian un factor de impacto mayor de 4. Conclusion: Las publicaciones sobre AA en Espana han experimentado un crecimiento exponencial en el periodo estudiado, sin evidencia de que se haya alcanzado un punto de saturacion.

16 citations


Journal ArticleDOI
TL;DR: Despite Australian publications on atypical antipsychotic drugs appearing in reasonably high impact journals, most were confined to a single Australian psychiatry journal and overall publications did not show exponential growth over the period studied.
Abstract: Objective:We performed a bibliometric study on scientific publications on atypical antipsychotic drugs (AADs) from Australia.Methods:Using the EMBASE and MEDLINE databases, we chose those documents...

12 citations


Journal ArticleDOI
TL;DR: The data confirmed that the pattern of the modulation of the acoustic startle reflex reveals appetitive effects of the alcohol cues and extended it to a variety of clinical variables.
Abstract: Cue modulation of the startle reflex is a paradigm that has been used to understand the emotional mechanisms involved in alcohol dependence. Attenuation of the startle reflex has been demonstrated when alcohol-dependent subjects are exposed to alcohol-related stimuli. However, the role of clinical variables on the magnitude of this response is unknown. The objective of this study was to determine the relationship between a number of clinical variables-severity of alcoholism, family history of alcoholism (FHA+), personality traits related to the sensitivity to reward-and the startle reflex response when subjects with alcohol dependence were viewing alcohol-related cues. After detoxification, 98 participants completed self-report instruments and had eye blink electromyograms measured to acoustic startle probes [100-millisecond burst of white noise at 95 dB(A)] while viewing alcohol-related pictures, and standardised appetitive, aversive and neutral control scenes. Ninety-eight healthy controls were also assessed with the same instruments. There were significant differences on alcohol-startle magnitude between patients and controls. Comparisons by gender showed that women perceived alcohol cues and appetitive cues more appetitive than men. Male and female patients showed more appetitive responses to alcohol cues when compared with their respective controls. Our patients showed an appetitive effect of alcohol cues that was positively related to severity of alcohol dependence, sensitivity to reward and a FHA+. The data confirmed that the pattern of the modulation of the acoustic startle reflex reveals appetitive effects of the alcohol cues and extended it to a variety of clinical variables.

11 citations


Journal ArticleDOI
TL;DR: The SGA publications in Japan have been through exponential growth over the studied period, without evidence of reaching a saturation point, according to Price’s law.
Abstract: Aims:Research on second-generation antipsychotic drugs (SGAs) has experienced great development in last decades.We did a bibliometric study on the scientific publications on SGAs in Japan.Methods: With theEMBASEandMEDLINEdatabases, we chose papers published from Japan with SGA descriptors. Price’s law and Bradford’s law has been used as bibliometric indicators for quantitating production and dispersion, respectively, of published papers on SGAs. We also calculated the participation index of different countries, and correlated those bibliometric data with some social and health data from Japan (such as totalper capitaexpenditure on health and gross domestic expenditure on research and development). Results: A sum of 669 original documents were published from Japan from 1982 to 2011. Those results fulfilled Price’s law, with scientific production on SGAs showing exponential growth (correlation coefficientr= 0.9261, as against anr= 0.8709 after linear adjustment). The most studied SGAs in Japan wererisperidone (n= 192), aripiprazole (n= 109), and olanzapine (n= 106). Division of documents into Bradford zones yielded a nucleus occupied exclusively by theProgress in Neuro-Psychopharmacology and Biological Psychiatry(49 articles). Those publications were in 157 different journals. Seven of the first 10 frequently used journals had an impact factor of being greater than 3. Conclusions: The SGA publications in Japan have been through exponential growth over the studied period, without evidence of reaching a saturation point.

9 citations


Journal ArticleDOI
TL;DR: The SGA publications in Hong Kong are still too few to confirm an exponential growth of scientific papers, and bibliometric indicators of Price's law and Bradford's law indicated non-fulfilment of Price’s law.
Abstract: Background: We did a bibliometric study on the scientific publications on second-generation antipsychotic drugs (SGA) in Hong Kong. Methods: With the EMBASE and MEDLINE databases, we chose those English articles from Hong Kong. We used bibliometric indicators of Price’s law for the increase of scientific literature, and of Bradford’s law for dispersion of papers. We also calculated the participation index of the different countries. Then, we correlated those bibliometric information with some social and health data (such as total per capita expenditure on health and gross domestic expenditure on research and development) of Hong Kong. Results: Forty-four original papers were published between 1993 and 2011. Our results indicated non-fulfilment of Price’s law (correlation coefficient r=0.5597 after exponential adjustment vs.r=0.6725 after linear adjustment). Those most widely studied SGA were clozapine (18 papers), risperidone (11 papers), and olanzapine (4 papers). Division into Bradford zones yielded a nucleus occupied by Journal of Clinical Psychopharmacology (4 articles) and Australian and New Zealand Journal of Psychiatry (4 articles). A total of 30 different journals were published. Conclusion: The SGA publications in Hong Kong are still too few to confirm an exponential growth of scientific papers.

6 citations


Journal ArticleDOI
TL;DR: Las intervenciones con familiares de pacientes dependientes del alcohol han demostrado su eficacia para mejorar el pronostico oficial de la dependen-cia alcoholica, basada en the colaboracion of los establecimientos publicos y asociaciones de pacients.
Abstract: Las intervenciones con familiares de pacientes dependientes del alcohol han demostrado su eficacia para mejorar el pronostico de la dependen-cia alcoholica. En la Comunidad de Madrid, la Federacion de exalcoholicos ha creado la Red de centros de alternativas psicosociales a las adicciones (Red CAPA) en cuyos dispositivos se atiende a los depen-dientes del alcohol y a sus familiares. El objetivo de este estudio ha sido el de demostrar que la integracion de terapias familiares mejoraba la sa-lud psicologica de los familiares y el pronostico del tratamiento de los pacientes dependientes. Fueron seleccionados 188 pacientes de nuestro programa del tratamiento del Hospital 12 de Octubre con sus respec-tivos familiares y se aleatorizaron en dos grupos. Un grupo A (n=94) recibia el tratamiento habitual para pacientes y familiares de nuestro programa de tratamiento, mientras que en un grupo B (n=94) los pacientes eran atendidos en nuestro programa de tratamiento pero sus familiares acudian a un grupo de familias de la Red CAPA. Al cabo de 12 semanas los familiares del grupo B tenian mejor salud psicologica y los pacientes tuvieron menos dias de consumo y menores tasas de aban-donos del programa de tratamiento que los del grupo A. Los grupos para familiares de la Red CAPA son utiles en mejorar la salud psicologica de los familiares y en mejorar el pronostico de la dependencia. La inte-gracion de estos centros dentro de los programas publicos de trata-miento del alcoholismo podria proporcionar una nueva forma de tratar el alcoholismo, basada en la colaboracion de los establecimientos publicos y asociaciones de pacientes.

5 citations