Showing papers by "Gan-Xin Yan published in 2006"

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Journal Article•DOI•

Blinded validation of the isolated arterially perfused rabbit ventricular wedge in preclinical assessment of drug-induced proarrhythmias.

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Tengxian Liu¹, Barry S. Brown², Ying Wu¹, Charles Antzelevitch, Peter R. Kowey³, Peter R. Kowey¹, Gan-Xin Yan¹, Gan-Xin Yan³ - Show less +4 more•Institutions (3)

Main Line Health¹, GlaxoSmithKline², Thomas Jefferson University³

01 Aug 2006-Heart Rhythm

TL;DR: This study provides a blinded evaluation of the isolated arterially-perfused rabbit wedge preparation demonstrating both a high sensitivity and specificity in the assessment of 13 agents with varying propensity for causing TdP.

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126 citations