Showing papers by "Gan-Xin Yan published in 2012"

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Journal Article•DOI•

Differentiating electrophysiological effects and cardiac safety of drugs based on the electrocardiogram: A blinded validation

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Tengxian Liu¹, Martin Traebert², Haisong Ju², Willi Suter², Donglin Guo¹, Peter Hoffmann², Peter R. Kowey¹, Peter R. Kowey³, Gan-Xin Yan⁴, Gan-Xin Yan¹, Gan-Xin Yan³ - Show less +7 more•Institutions (4)

Lankenau Institute for Medical Research¹, Novartis², Thomas Jefferson University³, Xi'an Jiaotong University⁴

01 Oct 2012-Heart Rhythm

TL;DR: Specific electrophysiological action and the consequent proarrhythmic potential of a drug can be accurately determined by analysis of drug-induced changes in ECG in the rabbit left ventricular wedge preparation.

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17 citations

Journal Article•DOI•

The funny current (If): is it a novel antiarrhythmic target to treat atrial fibrillation?

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Xiaolin Xue¹, Gan-Xin Yan², Gan-Xin Yan³•Institutions (3)

Xi'an Jiaotong University¹, Thomas Jefferson University², Lankenau Institute for Medical Research³

01 Feb 2012-Journal of Cardiovascular Electrophysiology

TL;DR: The Funny Current (If): Is it a Novel Antiarrhythmic Target to Treat Atrial Fibrillation?

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Abstract: The Funny Current (If): Is it a Novel Antiarrhythmic Target to Treat Atrial Fibrillation? XIAOLIN XUE, M.D.∗ and GAN-XIN YAN, M.D., Ph.D.†,‡ From the ∗Department of Cardiology, the First Hospital, Xi’an Jiaotong University, Xi’an, China; †Main Line Health Heart Center and Lankenau Institute for Medical Research, Wynnewood, Pennsylvania; and ‡Jefferson Medical College, Thomas Jefferson University, Philadelphia, Pennyslvania, USA

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4 citations