G
Gang Wu
Researcher at Purdue Pharma
Publications - 1
Citations - 256
Gang Wu is an academic researcher from Purdue Pharma. The author has contributed to research in topics: TRPV1 & Vanilloids. The author has an hindex of 1, co-authored 1 publications receiving 242 citations.
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N-(4-Tertiarybutylphenyl)-4-(3-chloropyridin-2-yl)tetrahydropyrazine -1(2H)-carbox-amide (BCTC), a Novel, Orally Effective Vanilloid Receptor 1 Antagonist with Analgesic Properties: I. In Vitro Characterization and Pharmacokinetic Properties
Kenneth J. Valenzano,Elfrida R. Grant,Gang Wu,Mohamed Hachicha,Lori Schmid,Laykea Tafesse,Qun Sun,Yakov Rotshteyn,Joseph Francis,James T. Limberis,Shiazah Malik,Edward R. Whittemore,D. Dianne Hodges +12 more
TL;DR: In vitro pharmacology of a high potency, selective VR1 antagonist that, unlike capsazepine, has potent blocking effects on low pH-induced activation of rat VR1 is described, making it a more suitable candidate for testing the role played by VR1 in rat models of human disease.