G
Gary N Black
Researcher at Northumbria University
Publications - 1
Citations - 189
Gary N Black is an academic researcher from Northumbria University. The author has contributed to research in topics: Phosphorylation & Glycoside hydrolase. The author has an hindex of 1, co-authored 1 publications receiving 180 citations.
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Structure and mechanism of a bacterial beta-glucosaminidase having O-GlcNAcase activity
Rebecca J. Dennis,Edward J. Taylor,Matthew S. Macauley,Keith A. Stubbs,Johan P. Turkenburg,Sam Hart,Gary N Black,David J. Vocadlo,Gideon J. Davies +8 more
TL;DR: Mutagenesis and kinetics studies show that the bacterial enzyme, very similarly to its human counterpart, operates via an unusual 'substrate-assisted' catalytic mechanism, which will inform the rational design of enzyme inhibitors.