This study evaluated the effect of Xylopia aethiopica on the histology and morphology of the liver and kidneys, using Albino Wistar rat as experimental model. Twenty-four rats irrespective of gender were used for the study and were divided into four groups of six rats each. Group 1 served as control and were fed with rat chows and distilled water, groups 2, 3 and 4 were treated with 100mg/kg, 200mg/kg, 300mg/kg of the aqueous extract of Xylopia aethiopica alongside rat chow and distilled water for 21 days. The result shows significant decrease in total body weight, liver weight, and kidney weight of the three Xylopia aethiopica treated groups. Histopathological findings examination of liver reveals a mild to acute hepatitis in treated rats. On the other hand, that of the kidney reveals a dose dependent interstitial nephritis in the treated rats. Findings of this study revealed that aqueous extract of Xylopia aethiopica possess some toxic effect on the liver and kidney. Indiscriminate ingestion of the extract of Xylopia aethiopica should be avoided.

Research Article Histomorphological Effects of Xylopia aethiopica on the Liver and Kidney of

The effect of Xylopia aethiopica leaves on body weight and growth performance was studied on growing Wistar rats. The study involved twenty-four rats of comparable sizes and weights ranging from 150 to 300g and divided into four groups of six rats each. Group A served as the control while groups B, C and D served as the test and received 1.2g, 3.0g and 6.0g per day of Xylopia aethiopica leaves respectively for 21 days. The feed intake and weights of both the test animal and control were monitored weekly. Results showed that during the 21 days of Xylopia aethiopica leaves administrations, the control (Group A) had a greater mean body weight than those of the test groups. On growth performance, the average daily growth increased in the control but decreased in the test groups in a dose dependent manner. On the other hand, the feed conversion rate (FCR) was observed to decrease with time in the control  compared to the test groups where it increased with time. Based on the findings of this study therefore, Xylopia aethiopica may possibly influence body weight and growth performances.Keywords: Growth, Feed Conversion Rate, Body weight, Xylopia aethiopica, Plants.

/pdf/the-effect-of-xylopia-aethiopica-leaves-on-body-weight-and-2elatjmqjy.pdf

GE Agbo

Papers

The Effect of Xylopia Aethiopica Leaves on Body Weight and Growth Performance